Effect of Thyroid Disorders on Nerve Conduction Studies in Females

Balasubramaniam, K (2015) Effect of Thyroid Disorders on Nerve Conduction Studies in Females. Masters thesis, Tirunelveli Medical College, Tirunelveli.

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Abstract

INTRODUCTION: The magnitude of thyroid disorders are increasing globally. In India also there is an increasing incidence even though India is in post iodination phase. Most commonly the thyroid disorder is due to autoimmune pathology. Thyroid disorders affect all systems of the body including nervous system. The affection of neuromuscular problems includes proximal myopathy and various peripheral neuropathies. The early detection of peripheral neuropathy before clinical manifestations using electrophysiological methods helps in prevention of morbidity associated with the complications. AIMS AND OBJECTIVES: This study was carried out to evaluate the changes in the abnormalities in nerve conduction parameters in thyroid disorders and to find out the magnitude of neuropathies. MATERIALS AND METHODS: The study was conducted at Tirunelveli Medical college hospital after ethical clearance. Proforma was filled in to follow the inclusion criteria and exclusion criteria. 22 hypothyroid,18 hyperthyroid and 25 normal individuals were selected for the study and written informed consent was obtained. The sensory conduction was performed in sural, median and ulnar nerves and motor conduction in tibial, median and ulnar nerves of left side using RMS EMG EP MARG II equipment. RESULTS AND DISCUSSION: The study found out predominant sensory involvement in both groups. Sensory neuropathy was present in 45.4 % and 61 % of hypothyroid and hyperthyroid individuals respectively. Sensorimotor neuropathy was present in 9.1 % and 5.5 % of hypothyroid and hyperthyroid individuals respectively. The study has diagnosed carpel tunnel syndrome in 36 and 17 % of hypothyroid and hyperthyroid individuals. The involvement of nerves in hypothyroidism is due to less active sodium potassium pumps and hyperthyroidism due to hypermetabolism. CONCLUSION: The study has highlighted the involvement of peripheral nerves in thyroid disorders and the role of electrophysiological studies in early detection of neuropathies. The study also suggests to evaluate thyroid function in carpal tunnel syndrome.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Thyroid disorders ; Nerve conduction ; females.
Subjects: MEDICAL > Physiology
Depositing User: Punitha K
Date Deposited: 24 May 2018 17:48
Last Modified: 27 May 2018 12:35
URI: http://repository-tnmgrmu.ac.in/id/eprint/8072

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