Evaluation of Brainstem Auditory Evoked Potential in Essential Hypertension

Priya, V (2015) Evaluation of Brainstem Auditory Evoked Potential in Essential Hypertension. Masters thesis, Kilpauk Medical College, Chennai.


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INTRODUCTION: Central nervous system dysfunctions are common in patients of essential hypertension.Arterial and arteriolar spasm in cerebral blood vessels may be responsible.Micro-infarctions are known to be responsible for dysfunction in heart, kidney ,brain and other tissues in patients of hypertension. Brainstem auditory evoked potentials are the potentials recorded from the ear &vertex in response to a brief auditory stimulation to assess the conduction through auditory pathway upto midbrain. This study will be executed to evaluate subclinical brainstem auditory evoked potentials abnormalities in essential hypertension. AIM AND OBJECTIVES: AIM OF THE STUDY: To evaluate Brainstem Auditory Response in Essential Hypertension. OBJECTIVE : 1. To use Brainstem auditory evoked potential as tool to measure the subclinical abnormalities in patients with Essential Hypertension. 2. To assess the latencies and interpeak latencies in patients with Essential Hypertension. MATERIALS AND METHODS: This study was conducted at the Institute of Physiology, Kilpauk Medical College, Chennai. Study Design: Case control study. Subject selection : Total sample size -80 , Essential hypertensive patients -40 ; controls – 40. INCLUSION CRITERIA: 1. Patients with Essential hypertension diagnosed by the department of medicine, Kilpauk Medical College. Male & Female between 40 – 60 years. 2. Written informed consent. Exclusion Criteria: 1. Ischemic heart disease. 2. Diabetes mellitus. 3. Cerebro vascular disease. 4. Alcoholism. 5. Any neurological diseases. 6. Renal disease. 7. Hearing impairment. 8. Drugs causing ototoxicity. 9. Vitamin deficiency. 10. Drugs causing neuropathy. 11. Thyroid disorders. 12. H/O Antiepileptics. CONCLUSION: It is concluded that rise in blood pressure affects sensory conduction in the auditory pathway in the brainstem it prolongs the latencies indicating more involvement of 8th Nerve. So, this study suggests that early screening by Electro Physiological Test may preferably be done to prevent the Hearing impairment at an early stage. It has been proved that BAEP is a valuable method to detect early involvement of auditory pathway. Hence it is considered as useful screening tests for hypertensive subjects. More detail investigations involving BAEP in relation to various diseases have to come up in future.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Brainstem Auditory Evoked Potential ; Essential Hypertension.
Subjects: MEDICAL > Physiology
Depositing User: Punitha K
Date Deposited: 24 May 2018 17:45
Last Modified: 27 May 2018 12:13
URI: http://repository-tnmgrmu.ac.in/id/eprint/8064

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