Viji, M (2015) A Study on Urinary Bacterial and Fungal Isolates and their Antimicrobial Susceptibility Pattern from Patients Undergoing Invasive Urological OP Diagnostic Procedures including Cystoscopy and Urodynamic Study. Masters thesis, Madras Medical College, Chennai.
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Abstract
OBJECTIVES: To isolate and identify the bacterial and fungal causative agents for post procedure of urinary tract infection in patients undergoing cystoscopy and urodynamic (UD) evaluation in a prospective survey. To study the association of ompT virulent gene for E.coli with significant colony counts. The tolerability and acceptance of and UD studies by patients have not been thoroughly documented. It would be helpful to be able to give such information to patients before performing these procedures. METHODS: A total of 200 patients seen as outpatients for Cystoscopy and Urodynamic studies to evaluate various indications were studied. A midstream urine sample was taken before,third day and seventh after the procedures and semiquantitative culture was employed for colony counts. Detection of virulent gene ompT for E.coli by conventional PCR. Patients were given a uestionnaire that inquired about the presence of lower urinary tract symptoms after the procedures. RESULTS: Of the 200 patients analyzed (Cystoscopy100, UD studies 100), 9 patients (4.5%) developed significant bacteriuria .E.coli (40.9%) was the commonest isolated organism. ompT gene was negative for E.coli with significant colony counts. Only 2 patients (2%) with significant bacteriuria symptoms. The association between patients who had symptoms with significant growth and underlying condition after the procedure (n = 2) was significant (P<0.05). ompT gene. CONCLUSIONS: Cystoscopy and Urodynamic studies are safe, well-tolerated procedures. The antibiotics for the transieint infection of these procedures is unnecessary, unless specific indications are present.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | outer membrane protein (ompT) ; polymerase chain reaction (PCR). |
| Subjects: | MEDICAL > Microbiology |
| Depositing User: | Punitha K |
| Date Deposited: | 23 May 2018 02:54 |
| Last Modified: | 27 May 2018 04:45 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/8025 |
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