Diagnostic Efficacy of Thin Prep Preparation (Liquid Based Cytology) in Comparison to Conventional Pap Smears as a Primary Screening Tool for Cervical Lesions

Premalatha, A (2015) Diagnostic Efficacy of Thin Prep Preparation (Liquid Based Cytology) in Comparison to Conventional Pap Smears as a Primary Screening Tool for Cervical Lesions. Masters thesis, Sree Mookambika Institute of Medical Sciences, Kulasekharam.

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Abstract

INTRODUCTION: Cancer of the uterine cervix is the leading cause of mortality and morbidity among women throughout the world. It is the second most common malignancy among women globally and third largest cause of cancer mortality in India after cancers of the mouth, oropharynx and oesophagus. AIMS AND OBJECTIVES: To study the changes in the cervical cytology smears in the age group of women between 25-60 years, and to compare the efficacy of liquid based cytology smears with conventional pap smears. MATERIALS AND METHODS: This is a cross sectional study done on 110 women from the OPD of Obstetrics and Gynecology. Conventional and liquid based cytology smears were taken from them. The cytology smears were reported according to the 2001 Bethesda system. RESULTS: In our study, maximum number of participants 65(59.1%) were in the age group of 41-50yrs and 13(11.8%) had history of chronic vaginal infection. Among the 110 conventional pap smears, unsatisfactory smears were 6 (5.5%), and there were no unsatisfactory smears in liquid based cytology. The most common finding in cervical smear cytology was inflammatory smears, followed by normal and atrophic smear. Abnormal epithelial lesions were detected more in liquid based cytology. CONCLUSION: It is concluded that thin prep liquid based cytology modality shows more intraepithelial lesions than conventional smears.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Cytology ; conventional pap smear ; liquid based cytology smear.
Subjects: MEDICAL > Pathology
Depositing User: Punitha K
Date Deposited: 19 May 2018 15:17
Last Modified: 22 May 2018 17:42
URI: http://repository-tnmgrmu.ac.in/id/eprint/8018

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