Kumudhini Priya, G (2015) Diagnostic Immunohistochemistry with Tissue Microarray Technique: A Pilot Study on Non Hodgkin Lymphoma. Masters thesis, Tirunelveli Medical College, Tirunelveli.
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Abstract
Non-Hodgkin lymphoma (NHL) is a collective term for a heterogeneous group of lymphoproliferative malignancies with differing patterns of behaviour and responses to treatment. Incidence of lymphoma has doubled in the past 4 decades and continues to increase. In the context of lymphomas, immunohistochemistry is used to classify, sub-classify and predict prognosis of several classes of lymphomas. Tissue microarray facilitates the analysis of molecular alterations in thousands of tissue specimens in a massively parallel fashion. This study was conducted in Department of pathology, Tirunelveli medical college in which tissue micro array was prepared using manual method from lymph nodes of 21 cases among which 20 were diagnosed as Non-Hodgkin lymphoma by histomorphology. All the cases were subjected for immunohistochemical analysis using CD3, CD20, CD5, and CD10 from which 19 cases were taken for classification and analysis based on recent WHO classification of lymphomas and leukemias.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Non Hodgkin lymphoma ; CD ; Immunohistochemistry ; Lymph node ; Tissue microarray ; WHO. |
| Subjects: | MEDICAL > Pathology |
| Depositing User: | Punitha K |
| Date Deposited: | 19 May 2018 15:15 |
| Last Modified: | 23 May 2018 01:54 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/8001 |
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