A Comparitive Study of Microalbuminuria between Prehypertensive and Normotensive Individuals

Arun Kumar, B (2015) A Comparitive Study of Microalbuminuria between Prehypertensive and Normotensive Individuals. Masters thesis, Tirunelveli Medical College, Tirunelveli.

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Abstract

BACKGROUND: The aim of the study is to look for the presence of microalbuminuria in two groups namely a prehypertensive group (BP 120- 139/80-89mmHg) and a normotensive group (BP <120/80mmHg) and to find out is there a significant difference in presence of microalbuminuria in both groups. Also to look for the other end organ damage such as diastolic dysfunction and fundus changes and to find out is there a significant difference in both the groups. METHODS: The study participants who were selected from ward patient’s attenders were divided into two groups based on their blood pressure measurement. A brief history was recorded. Urine albumin creatinine ratio for microalbuminuria, fundus examination for retinopathy and echocardiogram to detect diastolic dysfunction was done in all participants. Other relevant investigations were done. RESULTS: The distribution of microalbuminuria in two groups are 2% and 28% in normotensive and prehypertensive group respectively (‘p’ value is<0.001) which is statistically significant. The distribution of diastolic dysfunction is 32% in prehypertensive group while none had diastolic dysfunction in normotensive group (‘p’ value is 0.004) which is statistically significant. 60% of those participants with microalbuminuria had associated diastolic dysfunction also. CONCLUSION: End organ damage starts to occur even at a prehypertension stage of blood pressure. So screening for high BP should start early and if detected to be prehypertensive, life style modification should be strongly recommended.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Prehypertension ; Normotension ; Microalbuminuria ; Diastolic Dysfunction ; Hypertension ; End Organ Damage.
Subjects: MEDICAL > General Medicine
Depositing User: Punitha K
Date Deposited: 18 May 2018 18:56
Last Modified: 19 May 2018 03:18
URI: http://repository-tnmgrmu.ac.in/id/eprint/7946

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