A Study on Mortality Outcomes in ICU Patients with Sequential Organ Failure Assessment (SOFA) Score

Santha Kumar, R P S P (2015) A Study on Mortality Outcomes in ICU Patients with Sequential Organ Failure Assessment (SOFA) Score. Masters thesis, Coimbatore Medical Collegel, Coimbatore.


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PURPOSE OF THE PROJECT: This study intends to evaluate the usefulness of sequential organ failure assessment score (SOFA) in assessing organ dysfunction and risk of mortality in patients admitted to ICU. BACKGROUND: Outcome prediction is important in both clinical and administrative ICU management. It can be usefully applied to monitor the progress of an individual ICU. It also provides useful information on likely patient outcomes for critically ill patients and also for therapeutic decision making and using available resources efficiently. In an ICU setting serial organ function monitoring is important since there is a time to time variation in the general condition of the patient. Sequential Organ Failure Assessment (SOFA) is one such outcome prediction model to assess prognosis and mortality risk in ICU patients. DATA COLLECTION AND THE SOURCE: All adult patients admitted to the intensive care unit of Coimbatore Medical College Hospital will be included in the study. Blood samples will be collected from the patients admitted to the ICU for the investigations as per the data needed by the SOFA scoring system. Along with these, blood pressure monitoring and Glasgow coma scale evaluation will be done on admission and then for every 48 hrs, for six days or till the patient leaves the ICU either as survivor or non survivor, whichever occurs earlier. SAMPLING METHOD: Prospective observational cohort study. Case definition: Patients admitted to the ICU with suspected multi organ failure. RESULTS: The age group in this study ranges from 17 to 85. The study shows that above the SOFA score value of 12, there is a sharp increase in mortality rate. More than 85% of the non survivors had an increase in their SOFA scores during their stay in ICU. Admission SOFA and mean sofa are excellent predictors of mortality. Total SOFA provides information about severity of organ failure. Mechanically ventilated patients had a higher mortality rate compared to non ventilated patients. Presence of diabetes and hypertension did not show any significant association with mortality in our study. CONCLUSION: A rise in SOFA score is a strong predictor of mortality in ICU patients.

Item Type: Thesis (Masters)
Uncontrolled Keywords: sequential organ failure assessment(SOFA) ; Intensive care unit (ICU).
Subjects: MEDICAL > General Medicine
Depositing User: Punitha K
Date Deposited: 18 May 2018 18:56
Last Modified: 21 May 2018 02:10
URI: http://repository-tnmgrmu.ac.in/id/eprint/7943

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