A Study of Serum Zinc,Copper and Calcium in Pregnancy and Preeclampsia.

Ponnudhali, D (2006) A Study of Serum Zinc,Copper and Calcium in Pregnancy and Preeclampsia. Masters thesis, Madras Medical College, Chennai.

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Abstract

Deficient or excessive levels of minerals can be an adverse factor in human and animal Pregnancies, which for a long time have been correlated with many maternal complications. Minerals like zinc, copper and calcium have been documented to play an important role in Pregnancy and fetal outcomes. Trace elements like zinc and copper are essential for the normal growth and Development; they have been implicated in various reproductive events like preeclampsia, Infertility, pregnancy wastage, congenital anomalies, placental abruption, premature rupture of Membranes, neurological abnormalities, fetal deaths and low birth weights. Calcium is the Macronutrient that has been best studied in relationship to preeclampsia. Preeclampsia is a critically important disease of pregnancy, one of the major causes of Fetal and maternal morbidity and mortality throughout the world. It is diagnosed by new onset Of increased blood pressure, proteinuria occurring after 20 weeks of gestation and remission of These signs after delivery. Preeclampsia is associated with substantial risks. For the fetus these include intra-uterine Growth retardation, death and prematurity whereas the mother is at risk for seizures (eclampsia), renal failure, pulmonary edema, stroke and death. Despite considerable research, The cause or causes of preeclampsia remain unclear and there are no clinically useful screening Tests to identify women in whom it will develop. The cause of preeclampsia is multifactorial And involves both genetic and other factors. The role of various minerals like zinc, copper and calcium in relation to preeclampsia Have been studied in different populations, all over the world. There are many studies showing A lowering of serum zinc along with the rise in serum copper and ceruloplasmin levels. Low Serum calcium levels have often been associated with preeclampsia. Several calcium Supplementation trials have shown that the incidence of preeclampsia can also be reduced by Increasing the calcium intake. Hence the interest has developed to assess the above minerals in preeclampsia, in our Population. Therefore the present study has been undertaken with the view of establishing the Role of zinc, copper and calcium in preeclampsia by determining their levels in serum in Nonpregnant, normal pregnant and preeclamptic women.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Serum Zinc Copper ; Calcium Pregnancy ; Preeclampsia.
Subjects: MEDICAL > Biochemistry
Depositing User: Subramani R
Date Deposited: 03 Jul 2017 12:00
Last Modified: 03 Jul 2017 12:00
URI: http://repository-tnmgrmu.ac.in/id/eprint/781

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