Blood Glucose Levels and Dyslipidemia in Chronic Periodontitis Patients: A Case Control Study

Baggialaxmi, S M (2010) Blood Glucose Levels and Dyslipidemia in Chronic Periodontitis Patients: A Case Control Study. Masters thesis, Tamilnadu Government Dental College and Hospital, Chennai.


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BACKGROUND: Several studies have indicated that subjects with periodontal disease may have a higher risk for cardiovascular disease when compared to subjects with a healthy periodontium (Mattila et al 1989, Beck et al 1998, Loesche 1998). Also, Periodontitis & Cardiovascular disease may share common risk factors such as Smoking, Diabetes, Ageing, and Male genders. AIM OF THE STUDY: To measure the level of fasting plasma lipid profile and blood glucose levels in chronic periodontitis patients and compare and correlate the results with those obtained in age and sex matched healthy individuals. MATERIALS AND METHODS: 30 subjects with chronic periodontitis divided into mild, moderate and severe study group based on CAL and 30 age and sex matched healthy controls participated in this study. Venous blood sample was collected by experienced trained person in the morning after an overnight fast and analyzed for serum triglycerides, total cholesterol LDL, HDL and blood glucose in the study and control group. Periodontal parameters, namely, probing pocket depth and CAL were recorded on full mouth basis at 6 sites per tooth. All measurements were made using William’s periodontal probe in both study and control group. RESULT: Triglycerides were significantly higher in periodontally diseased subjects (P<0.000) when compared with controls. When the mild, moderate and severe periodontitis patients in the study group were clumped as one group and compared with controls, statistically significant values were obtained for Total Cholesterol (P<0.002)and Triglycerides (P<0.000). Also, we found significantly higher values in blood glucose levels in patients than in the control group. CONCLUSION: It is likely that severity and poor control of periodontal disease might affect the level of lipids and glucose in blood which may increase the risk for CVD. Therefore, when periodontitis is newly diagnosed in patients with atherosclerotic CVD, periodontists and physicians managing patients with CVD should closely collaborate to optimize CVD risk reduction & periodontal care.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Blood Glucose Levels ; Dyslipidemia ; Chronic Periodontitis Patients ; Case Control Study
Subjects: DENTAL > Periodontology
Depositing User: Kambaraman B
Date Deposited: 13 May 2018 02:18
Last Modified: 13 May 2018 02:21

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