Improved Bioavailability of Rifampicin Nanoparticles from Fixed Dose Combination with Isoniazid, Pyrazinamide and Ethambutol.

Rajasekhar, Pasupuleti (2014) Improved Bioavailability of Rifampicin Nanoparticles from Fixed Dose Combination with Isoniazid, Pyrazinamide and Ethambutol. Masters thesis, Swamy Vivekanandha College of Pharmacy, Tiruchengode, Tamilnadu, India.

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Abstract

The Present study aimed to improve the bioavailability of Rifampicin from fixed dose Combination with Isoniazid, Pyrazinamide and Ethambutal by Incorporating Rifampicin Nanoparticles with fixed dose Combinations. Rifampicin Nanoparticles were Prepared With different Concentrations of PLGA as Polymer and it was evaluated for its physico chemical parameters such as FTIR ,DSC, Entrapment Efficiency, Loading Capacity, In vitro drug release and In vivo pharmacokinetics. The percentage formation of its metabolite (3FRSV) also studied.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Improved Bioavailability; Rifampicin Nanoparticles; Fixed Dose; Isoniazid; Pyrazinamide; Ethambutol
Subjects: PHARMACY > Pharmaceutics
Depositing User: Ravindran C
Date Deposited: 02 Jul 2017 09:31
Last Modified: 02 Jul 2017 09:31
URI: http://repository-tnmgrmu.ac.in/id/eprint/765

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