Rajesh, B (2015) A Comparative Study of Dexmedetomidine Induced Hypotension for Functional Endoscopic Sinus Surgery. Masters thesis, Chengalpattu Medical College, Chengalpattu.
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Abstract
OBJECTIVE: To compare the effectiveness and advantages of using dexmedetomidine and esmolol in induced hypotension for functional endoscopic sinus surgery. METHODS: Fifty patients belonging to ASA 1 planned for functional endoscopic sinus surgery were randomly divided into two group’s. Dexmedetomidine group received a bolus dose of 1 microgram/kg over 10 minutes followed by infusion at a rate of 0.4-0.8 microgram /kg/hr. Esmolol group received a bolus dose of 1 mg/kg over one minute followed by infusion at a rate of 0.4-0.8mg/kg/hr. The target mean arterial pressure was 55-65 mm hg. General anaesthesia was maintained with 60% N20:O2. Induction dose of propofol, haemodynamic variable’s (blood pressure and heart rate), intra operative serum cortisol, quality of surgical field, emergence time, post anaesthesia recovery score(modified aldrete score >9), sedation score at 15, 30 and 60 minute’s, time for rescue analgesia were recorded. RESULT Dose of propofol was lower in dexmedetomidine group than esmolol group. Heart rate and blood pressure were comparable in both groups intra operatively, when target mean arterial was achieved. Quality of surgical field and intra operative serum cortisol level’s were comparable in both group’s. Emergence time and time to achieve aldrete score > 9 were higher in dexmedetomidine group than esmolol group. Sedation score’s were higher in dexmedetomidine group than esmolol group at 15, 30 minute’s post operatively. Time for rescue analgesia was prolonged in dexmedetomidine group than esmolol group. CONCLUSION: The use of dexmedetomidine in induced hypotension for functional endoscopic sinus surgery has additional advantage of sedative, analgesic and reduced requirement of anaesthetic agent’s than esmolol.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Dexmedetomidine Induced Hypotension ; Functional Endoscopic Sinus Surgery. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Punitha K |
| Date Deposited: | 07 May 2018 05:10 |
| Last Modified: | 08 May 2018 02:36 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7596 |
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