Vasanthy, J (2015) A Comparative Study of the Effect of Clonidine Tramadol and Nalbuphine on Postspinal Anaesthesia Shivering. Masters thesis, Thanjavur Medical College, Thanjavur.
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Abstract
OBJECTIVES: To compare the efficacy of Tramadol, Nalbuphine, and Clonidine in the treatment of shivering after spinal anaesthesia in caesarean section. METHODS: A prospective randomised comparative study was conducted between 1.8.2013 to 1.9.2014 to compare the efficacy of Tramadol, Nalbuphine, Clonidine in treatment of shivering after spinal anaesthesia in casearean section. Patients included in this study are those who developed shivering after spinal anaesthesia for caesarean section. Patients were randomly allotted to one of the three groups, namely T group (25) who received Tramadol 0.5mg/kg i.v., N group (25) who received Nalbuphine 0.1mg/kg i.v and C group (25)who received clonidine 0.5μg/kg iv. Vital parameters of the patient such as H.R. B.P. SPO2, RR and temperature were monitored at regular intervals as per protocol. Events such as onset of shivering, time taken to stop shivering, recurrence of shivering and side effects like nausea, vomiting bradycardia, hypotension and sedation were also noted. Statistical tests like chi square test, Anova test were applied to the data collected. RESULTS: Among the 75 patients who developed shivering of grades 3 & 4 requiring treatment were randomly allotted to one of the three group. The mean temperature at which patient developed shivering was 36.4°C, and the mean duration of shivering to occur following spinal anaesthesia was 22.5 mts. Tramadol 0.5 mg/kg controlled shivering in mean time of 4 minutes, clonidine 0.5 μg/kg, controlled shivering in mean time of 2 minutes and Nalbuphine 0.1 mg/kg controlled shivering in mean time of 4 minutes. CONCLUSION: Our study concludes that all three drugs namely Tramadol clonidine and nalbuphine were effective in controlling postspinal anesthesia shivering. Among them clonidine took lesser time to achieve complete cessation of shivering and also maintained better hemodynamics throughout the study.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Shivering ; Spinal anaesthesia ; Nalbuphine ; Tramadol ; clonidine. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Punitha K |
| Date Deposited: | 07 May 2018 04:57 |
| Last Modified: | 08 May 2018 02:57 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7593 |
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