Karthikeyan, M (2015) Pulmonary Function Tests in Type 2 Diabetic Patients Undergoing Major Abdominal Surgeries under General Anesthesia: A Study of 100 Cases. Masters thesis, Madurai Medical College, Madurai.
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Abstract
BACKGROUND: Diabetes mellitus is a systemic disease. Among the various organs affected by diabetes, lung is also included. Pulmonary function tests can be assessed by spirometry preoperatively which helps in better outcome of the diabetic patients postoperatively. AIMS AND OBJECTIVES: The aim of the study is to evaluate the pulmonary function tests in type 2 diabetic patients undergoing elective major abdominal surgeries under general anesthesia. MATERIALS AND METHODS: Fifty type 2 diabetic patients and fifty non-diabetic patients in the age group of 40-60 yrs undergoing elective major abdominal surgeries under general anesthesia were selected for the study. General anesthesia was standardised for both the groups. Pulmonary function tests were performed 60 minutes before and 60 minutes after the end of surgery. In the diabetic group, patients with duration of diabetes of 5-15 yrs were selected for the study. The pulmonary function tests recorded were FEV1, FVC, FEV1/FVC, FEF 25%, Peak expiratory flow rate (PEFR). RESULTS: The pulmonary function tests were significantly reduced in diabetic patients both preoperatively and postoperatively when compared to non-diabetic patients. CONCLUSION: Diabetes mellitus being a systemic disease,affects lungs causing ventilatory abnormalities probably because of glycosylation of connective tissues, reduced pulmonary elastic recoil and inflammatory changes in the lungs.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Diabetes mellitus ; Pulmonary function tests ; General anesthesia. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Punitha K |
| Date Deposited: | 07 May 2018 04:04 |
| Last Modified: | 08 May 2018 06:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7577 |
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