Stalin, R (2015) A Prospective Randomized Controlled Study to Compare Application of Betamethasone Gel and Lidocaine Jelly on Tracheal Tube to Reduce Post Operative Sore Throat, Cough and Hoarseness of Voice. Masters thesis, Madras Medical College, Chennai.
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Abstract
BACK GROUND AND OBJECTIVES: Endotracheal intubation often gives way to airway mucosal traumatization resulting in post operative sore throat, cough and hoarseness of voice [POSTCH]. These are minor sequelae after extubation but very distressing to the patient. Many agents have been used on the endotracheal tube to reduce the occurrence of POSTCH with variable results. This randomized controlled study was conducted to compare the incidence of POSTCH with betamethasone gel and lidocaine jelly as a lubricant for tracheal tube insertion in patients undergoing general anesthesia. METHODS: This study was conducted on three hundred American Society of Anaesthesiologist [ASA] class I and II patients undergoing elective general, orthopaedic and ear a surgeries. They were divided equally into three groups.100 patients [group-I], 100 patients [group II] and 100 control [group III]. The tracheal tubes for group I were lubricated with 0.05 % betamethasone gel, for group II lidocaine 2% jelly was used and for control group III nothing was applied. A blinded anaesthesiologist interviewed all patients regarding POSTCH at 1,6,12 and 24 hours after surgery. RESULTS: The mean score for sore throat in group I was always lower than mean scores in group II and III at all the specified time intervals over the 24 hour evaluation period. The P value was < 0.05 over all the four evaluation periods and hence it was statistically significant. In addition, at 24 hours, the mean score was comparable between the groups II and III.As P value is > 0.05, there was no statistically significant difference between group II and group III. The mean scores for cough was similar in group I and II at 1,6 and 24 hours. There was no statistically significant difference between group I and II since the P value is >0.05.The cough was less in group I and II when compared to group III at 1,6 and 24 hrs but at 12 hrs there was no statistically significant difference between all the three groups [P value > 0.05]. The mean scores for hoarseness in group I was always lower than mean scores in group II and III at all the specified time intervals over the 24 hour evaluation period. The P value was less than 0.05 over all the four evaluation periods and hence it was statistically significant. INTERPRETATION AND CONCLUSION: From the present study it can be concluded that betamethasone gel application on endotracheal tube significantly reduces post operative sore throat when compared to lidocaine jelly but the lidocaine jelly has got a comparable effect as betamethasone gel in reducing post operative cough and hoarseness of voice.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Endotracheal intubation ; POSTCH ; betamethasone ; lidocaine. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Punitha K |
| Date Deposited: | 07 May 2018 03:30 |
| Last Modified: | 07 May 2018 03:30 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7564 |
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