Kavitha, C (2015) A Study of Neurological Soft Signs in Positive and Negative Subtype of Schizophrenia. Masters thesis, Madras Medical College, Chennai.
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Abstract
BACKGROUND AND OBJECTIVES: Soft neurological signs have been observed in patients with schizophrenia. There are several studies demonstrating neurological impairments in schizophrenia patients but their presence has been complicated by a number of potentially confounding variables such as the duration of the illness, medication doses and the use of different measurement techniques. Soft neurological signs appear to be a trait feature of schizophrenia as well as a possible biological marker of its prognosis. Therefore, their early detection and the consequent early intervention may lead to a better prognosis. Assessment of the soft neurological signs is a direct, easily administered and inexpensive way of investigating the severity of brain dysfunction in schizophrenia. The co-relation between the positive and negative subtype of schizophrenia and soft neurological signs in a patient has not been extensively studied in the context of the Indian population. Therefore, this study aims to evaluate the presence of soft neurological signs in patients diagnosed with schizophrenia. METHOD: Sixty subjects, 30 patients with Positive schizophrenia and 30 patients with Negative schizophrenia were evaluated. Tools used were PANSS for evaluation of symptomatology in schizophrenia patients, NES for evaluation of neurological soft signs, Self structured proforma for assessing socio demographic status. Statistics Used: Students t test χ2 (Chi-square), Binary Logistic Regression, with the help of the statistical package namely IBM SPSS Statistics-20. RESULTS: Socio-demographic variables and clinical variables like age gender, educational status, duration of illness have no correlation with presence of soft neurological signs in patients with schizophrenia. Statistically there is no significant positive correlations are observed between the negative and positive symptom subscale of PANSS and the NES scores. Among the NES Subscales, sensory integration and Others items in NES score are Statistically significantly positive in negative type of schizophrenic patients schizophrenia. CONCLUSIONS: Soft neurological signs are observed in adult patients with schizophrenia and the presence of these signs are not correlated with both positive and negative syndrome of schizophrenia.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Schizophrenia ; Soft neurological signs ; NES |
| Subjects: | MEDICAL > Psychiatry |
| Depositing User: | Punitha K |
| Date Deposited: | 05 May 2018 13:34 |
| Last Modified: | 05 May 2018 13:34 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7503 |
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