Formulation and Evaluation Valsartan Angiotensin Receptor Blocker.

Sahaya Arockiadass, A S (2014) Formulation and Evaluation Valsartan Angiotensin Receptor Blocker. Masters thesis, Edayathangudy G.S Pillay College of Pharmacy, Nagapattinam, Tamil Nadu, India.


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The colloidal drug carriers have the potential to afford site specific as well as targeted drug delivery. The idea of using submicron drug delivery systems for drug targeting was conceived and developed after Paul Ehrlich originally proposed the idea of tiny drug-loaded magic bullets over a hundred year ago. Among these carriers, liposomes and micro/nanoparticles have been the most extensively investigated. Liposomes present some technological limitations including poor reproducibility and stability, and low drug entrapment efficiency. Nevertheless, several low molecular weight drugs are now commercially available which employ this technology. Stability studies were carried out to find out the stability and changes in appearance and entrapment efficiency for optimized formulation F6. The formulation was stored at 30±2°C/65±5% RH for two months. The results were shown Table 5 and figure 14. The results showed that there was no significant difference in appearance and entrapment efficiency.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Formulation; Evaluation; Valsartan; Angiotensin Receptor Blocker
Subjects: PHARMACY > Pharmaceutics
Depositing User: Ravindran C
Date Deposited: 30 Jun 2017 10:05
Last Modified: 30 Jun 2017 10:05

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