Kalaivani, R (2008) A Study on Malaivembu Ilai Chooranam and Paavana Omum. Masters thesis, Government Siddha Medical College, Chennai.
|
Text
320201508kalaivani.pdf Download (661kB) | Preview |
Abstract
MALAIVEMBU ILAI CHOORANAM 1. The trial drug Malaivembu Ilai Chooranam has been selected for anti diabetic activity based on strong literary evidence. i) After obtaining guidance for the Head of the department and permission from principal, Government siddha medical college. Pharmacological study was carried out in C.L. Baid Metha college of pharmacy, Thoraipakkam, Chennai. ii) The single drug was prepared as chooranam then purified and stored. 2. Phytochemical tests showed the presence of alkaloids, flavanoids, tannin and phytosteroids. 3. Rf values were determined by Thin Layer Chromatography. 4. Antimicrobial study proved that Malaivembu Ilai Chooranam was an effective anti bacterial agents. 5. Bio-Chemical analysis shows the presence of elements like zinc, calcium and Iron (Ferrous). 6. Malaivembu Ilai Chooranam at the dose of 2000mg/kg/po did not exhibit any mortality in mice. 7. Animal experiments revealed that this drug is effective in controlling blood sugar levels significantly when given in a dose of 500mg bds with water before food. 8. Clinical trial showed that Malaivembu Ilai Chooranam is effective in reducing both the fasting and postprandial blood sugar levels. It was done in Arignar Anna Hospital of Indian medicine, Chennai – 106. 9. The statistical analysis also significantly shows the reduction of symptoms like polyuria, tiredness, polydipsia, polyphagia, giddiness and peripheral neuritis. 10. The administration of Malaivembu Ilai Chooranam for 48 days did not produce any side effects. Out of 40 patients 33 patients showed better response in reduction at symptoms like polyuria, polydipsia, polyphagia, fatigue and giddiness. Moderate response in peripheral neuritis. 11. The trial drug is available at everywhere in all seasons. The preparation and preservation of the trial drug is simple and economical. So it is concluded that Malaivembu Ilai Chooranam has antidiabetic activity and moderately effective for controlling blood sugar levels. PAAVANA OMUM: The trial drug Paavana Omum has been selected for its antiulcer activity bases on literature evidence. 1. Bio- Chemical analysis shows the presence of elements Copper, Magnesium, calcium and Iron (ferric) 26. (i) Copper has ulcer healing property. (ii) Mg – Magnesium Hydroxide that neutralize the HCL. (iii) Ca is in the form of CaCl2 in the stomach. It is a antacid. 2. Animal experiments revealed that drug has a ulcer healing property when given in a dose of 500mg bds with water before food. 3. Clinical trial showed that Paavana omum is effective. 4. The Statistical analysis also significantly shows the reduction of symptoms like epigastric pain, heartburn, regurgitation, nausea, vomiting and abdominal distension. 5. The administration of Paavana Omum for 48 days did not produce any side effects. 6. Out of 40 patients, 30 patients showed better response in reduction at symptoms like epigastric pain, heartburn, regurgitation, nausea, vomiting, and abdominal distension. 7. So it is concluded Paavana Omum has antiulcer activity.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg. No. : 32051603 |
| Uncontrolled Keywords: | Malaivembu Ilai Chooranam ; Paavana Omum. |
| Subjects: | AYUSH > Gunapadam |
| Depositing User: | Kambaraman B |
| Date Deposited: | 20 Apr 2018 01:18 |
| Last Modified: | 29 Dec 2018 15:21 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7135 |
Actions (login required)
 |
View Item |
