Gracia Christy Priya, J (2008) A Study on Avuri Ilai (Indigofera tinctoria L.) for Azhal Keel Vayu and A Study on Ukkira Veera Chenduram for Mathumegam. Masters thesis, Government Siddha Medical College, Chennai.
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Abstract
The study on Avuri ilai choornam to evaluate its efficacy in the management of Azhal Keel Vayu was carried out based on the evidences collected from Siddha literature. The Pharmacognostic study was carried out at Central Research Institute for Siddha, Chennai-106 and C.L.Baid Metha College of Pharmacy, Thoraipakkam, Chennai. The single drug was prepared as Choornam, then purified and stored. Phytochemical tests showed the presence of Alkaloids, Flavanoids, Tannins and Phytosterols. Rf values were determined by Thin layer chromatography. Bio chemical analysis showed presence of Calcium, Phosphorus, Iron (Ferrous), Sulphate and Chloride. Anti-microbial study proved it to be an effective antibacterial agent. Pharmacological study was done for its anti-inflammatory and analgesic activities at C.L.Baid Metha college of Pharmacy, Thoraipakkam, Chennai. Choornam produced significant anti-inflammatory and analgesic activity. Clinical assessment was carried out as an open clinical trial in the PG Gunapadam department at Arignar Anna College and Hospital for Indian medicine, Chennai. The patients were selected according to selection criteria. Patients were carefully observed in regular visits and prognosis was documented. Sex distribution, socio-economical status, occupational status was assessed. Avuri ilai Choornam, 1gm, was administered twice a day with lukewarm water after food, for a period of 48 days. In the clinical trial, improvement in signs and symptoms like pain in the affected joint, swelling, joint tenderness were clinically and statistically significant. No adverse effect was observed during course of study. CONCLUSION: The evaluation of the efficacy of the single drug Avuri ilai Choornam in the management of Azhal Keel Vayu gave significant results. Presence of alkaloids and flavanoids play a vital role in the management of Azhal keel vayu. Pharmacological anti-inflammatory and analgesic activities strengthen the study. Clinically the drug relieved the symptoms, pain, swelling, joint tenderness and restriction of movements. Avuri ilai choornam with its vehicle regularised the three humors by stabilizing the pitha thathu and vatha thathu by its kaippu suvai. No adverse effects were observed during the period of study. In total, Avuri ilai Choornam plays a potential therapeutic role in management of Azhal Keel Vayu. Avuri ilai Choornam needs further study with regard to the mechanism of action to develop it as a potent anti-inflammatory and analgesic agent.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg. no: 32051602 |
| Uncontrolled Keywords: | Avuri Ilai (Indigofera tinctoria L.) ; Azhal Keel Vayu ; Ukkira Veera Chenduram ; Mathumegam. |
| Subjects: | AYUSH > Gunapadam |
| Depositing User: | Kambaraman B |
| Date Deposited: | 20 Apr 2018 01:14 |
| Last Modified: | 29 Dec 2018 15:01 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/7134 |
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