Reghupathy, P (2013) Serum Zinc Level in Children admitted with Pneumonia in a Tertiary Care Hospital. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION: In the past thirty years the total number of children dying within five years of life has come down by almost one third. But this decrease in mortality rate has not been the same throughout the globe. Infectious diseases still kill huge number of children in low income countries. This problem is augmented by co existing malnutrition, both forming a deadly combination kill considerable number of children in the young age. Each year greater than ten million children loss their life within five years of age in developing countries.(1) Pneumonia is defined as an inflammation of the lung parenchyma. Pneumonia is the most common cause of death in children worldwide and every year around 1.2 million under five children die because of pneumonia.(1)It accounts for eighteen percent of all under five years deaths including non infectious cause Pneumonia is more common in south Asia and sub-Saharan Africa (1) Incidence of pneumonia in south Asia is 0.36 episodes per Child per year as compared to 0.26 for world and 0.03 for industrialized countries. (3). This illustrates the prevalence of organisms and risk factors for pneumonia such as over crowding and malnutrition AIM OF THE STUDY: To compare serum zinc level in children with Severe pneumonia with age, sex and nutritional matched controls. DISCUSSION: There is no significant difference between the mean serum zinc levels between different age group of children admitted with pneumonia. (p=0.826). This is similar to the findings of previous studies (15,17). The mean serum zinc level in all age group admitted with pneumonia have are low when compared to controls. It is statistically significant in all sub age group except in children greater than 25 months. In this age group though serum zinc level is low it is not statistically significant and it may be due to less number of children recruited in this age group. Studies done in serum zinc level in pneumonia ,diarrhoea showed similar results that age is not a confounding factor in serum zinc in pneumonia. It is observed in all studies irrespective of geographical area namely north India (15), turkey(16) except a study done at Pakistan (17) where puspha et al showed low serum zinc level in infant age. Comparison of mean serum zinc level between male and female children recruited in this study doesn’t showed any significant difference. There is no significant difference between mean serum zinc level of both sexes in children admitted with pneumonia (p=0.700). Both male and female children with pneumonia have statistically low mean serum zinc level compared to controls. Most of the published data (15, 16, 17) had similar results. They all had similar finding that there was no statistical significant difference in serum zinc level between both sexes.CONCLUSION: Serum zinc levels are significantly low in children with severe pneumonia compared with age, sex and nutritionally matched controls.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Serum Zinc Level ; Children ; Pneumonia ; Tertiary Care ; Hospital. |
| Subjects: | MEDICAL > Paediatrics |
| Depositing User: | Ravindran C |
| Date Deposited: | 06 Apr 2018 09:09 |
| Last Modified: | 12 Apr 2018 10:05 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/6901 |
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