Prospective Randomized Comparison of Intrathecal 0.5% Bupivacaine with addition of Pethidine, Fentanyl, Tramadol Versus Placebo in Preventing Perioperative Shivering in Endoscopic Urological Surgeries

Nivedhyaa, S (2013) Prospective Randomized Comparison of Intrathecal 0.5% Bupivacaine with addition of Pethidine, Fentanyl, Tramadol Versus Placebo in Preventing Perioperative Shivering in Endoscopic Urological Surgeries. Masters thesis, Madras Medical College, Chennai.

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Abstract

SUMMARY: From this prospective, randomised, single blinded study we have evaluated the effectiveness of intrathecal opioid in reducing shivering in endoscopic urological surgeries. The following points were observed and noted during the study and statistical analysis: The demographic profile like Age, Sex, and Surgery: TURP and URS, Weight and Height were comparable between the four groups and did not show any statistical significance. The incidence and intensity of shivering was less in the opioid group than in the control group. Amongst the opioids, the intensity of shivering was least in Group P at all times and more in Group F. The incidence of shivering were similar in Group F and in Group C. The incidence of generalised shivering (grade 4) was more in Group F than in Group C. The mean sublingual temperature was lowest in the Group T at the end of T50 and T1H. At all other time intervals, sublingual temperature was comparable between all four groups. This infers that the addition of opioid did not increase the propensity for hypothermia The hemodynamic parameters, the occurrence of nausea, vomiting and pruritus, duration of the procedure, level of sensory block, intravenous fluid and irrigation fluid were comparable amongst the four groups. CONCLUSION: The addition of intrathecal opioid to bupivacaine for spinal anaesthesia reduces the incidence and intensity of shivering in endoscopic urological surgeries. • Intrathecal Pethidine is more efficacious than intrathecal Tramadol and intrathecal Fentanyl in reducing intraoperative and postoperative shivering. • Thus intrathecal Pethidine can be used prophylactically to reduce shivering and it maintains hemodynamic stability particularly in patients who have a diminished cardio respiratory reserve. • Intrathecal Fentanyl was not as efficacious in controlling shivering.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Prospective Randomized Comparison ; Intrathecal 0.5% Bupivacaine ; Pethidine ; Fentanyl ; Tramadol ; Placebo ; Preventing Perioperative Shivering ; Endoscopic Urological Surgeries.
Subjects: MEDICAL > Anaesthesiology
Depositing User: Kambaraman B
Date Deposited: 04 Apr 2018 17:45
Last Modified: 04 Apr 2018 17:45
URI: http://repository-tnmgrmu.ac.in/id/eprint/6843

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