Senthil, A N (2009) Microvascular Complications and Metabolic Syndrome in Newly Diagnosed Type 2 Diabetics of Low Socio-Economic Group. Masters thesis, Madras Medical College, Chennai.
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Abstract
CONCLUSION: Prevalence of microvascular complications in newly diagnosed diabetics of low socioeconomic group were as follows: symptomatic neuropathy – 57.3%, objective neuropathy – 39.8%, retinopathy – 4.9%, nephropathy – 18.4%. These were similar to published studies from general population from the same geographical area. • Prevalence of metabolic syndrome (76.6%) and measures of obesity in newly diagnosed diabetics in an unexpected manner had a similar trend in low socioeconomic group when compared to data from various studies among general population. • Significant association (P < 0.01) was noted between metabolic syndrome and sex with an increasing trend in females. Similarly association (P < 0.05) was found between metabolic syndrome and diastolic blood pressure, HDL and BMI. • Majority of females of low socioeconomic group had high BMI (89%), and had high prevalence of metabolic syndrome (87.3%) when compared to males of the same class. Significant association (P < 0.01) was found between sex and lifestyle with majority of females leading a sedentary lifestyle. 65 • High prevalence of family history (55.3%) indicates that genetic component could play a major role in the pathogenesis of diabetes in low socioeconomic group diabetics. • Average generation gap for onset of diabetes based on clinical diagnosis was 16 years in low socioeconomic group. • Only 23.6% of subjects presented themselves for screening and 76.7% of diabetics were detected by chance during health visits to doctor for some other disease. SUMMARY: Microvascular complications and metabolic syndrome are well known facts related to type 2 diabetes. However there is paucity of data regarding the disease characteristics in low socioeconomic group. This is the reason for designing a cross sectional study of this type. Aims and objectives were to find the prevalence of microvascular complications and metabolic syndrome in newly diagnosed type 2 diabetics of low socioeconomic group. Another objective of this study was to find out the generation gap of onset of diabetes in low socio economic group. The data was collected from a sample of 103 newly diagnosed diabetic subjects belonging to low socioeconomic group. The data was analyzed statistically. The results of the study revealed a prevalence of symptomatic neuropathy (57.3%), objective neuropathy (39.8%), retinopathy (4.9%), nephropathy (18.4%) and metabolic syndrome (76.6%). Sex, diastolic blood pressure, HDL and lifestyle were important risk factors associated with metabolic syndrome in this study. One would expect a higher prevalence of microvascular complications in low socioeconomic group, because of the tendency to seek the health facility after a delayed period. This is due to lack of awareness about symptoms of diabetes and its complications and low educational level. Also another expectation is lower prevalence of metabolic syndrome in low socioeconomic group since they consume less calorie rich diet and involve in labour intense jobs. However, contrary to these expectations the prevalence of microvascular complications was similar in trend with the studies from general population in the same geographical area. Also the prevalence of metabolic syndrome was similar to the trend observed from studies in general population in India. Hence low socioeconomic group people are not different from general population as far as microvascular complications or metabolic syndrome is concerned. They should be subjected to screening for microvascular complications at the time of diagnosis itself. Low socioeconomic group females were at more risk of diabetes and cardiovascular disease because of metabolic syndrome, obesity risk factors, and sedentary lifestyle when compared to males. Future health policies of the government targeting low socioeconomic group population should focus more on creating awareness, not only about diabetes and its complications but also about promoting active lifestyle. Since the onset of diabetes was one to two decades earlier in subsequent generations in this study and majority of the study subjects were diagnosed by chance during health visits for other diseases, focus should be more on detecting cases earlier by targeted screening and initiating appropriate prevention strategies.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Microvascular Complications ; Metabolic Syndrome ; Newly Diagnosed Type 2 Diabetics ; Low Socio-Economic Group. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 28 Mar 2018 05:28 |
| Last Modified: | 31 Mar 2018 02:29 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/6690 |
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