Kamatchi, K (2009) Prevalence of Carotid Artery Stenosis in Acute Ischaemic Stroke Patients. Masters thesis, Madras Medical College, Chennai.
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Abstract
SUMMARY: 1. 75 Acute ischaemic stroke patients with CT-Brain showing infarcts were taken for the study. 2. Age, Sex, History of DM, HT, Smoking, FBS and Fasting lipid profile were recorded for the subjects. 3. They were subjected to Doppler Ultrasonography of the carotid arteries which is a cost effective and non-invasive method to detect atherosclerotic plaque, carotid stenosis and to measure the degree of stenosis. 4. 35 patients had carotid stenosis. The prevalence of carotid stenosis in our study was 46%. The prevalence of mild, moderate and severe stenosis were 17%, 16% and 13% respectively. 5. The distribution of carotid stenosis was equal on both sides and ICA (71%) was the common site of atherosclerotic plaque and stenosis. 6. There was a statistically significant correlation between increasing age, male gender, smoking, DM, HT, and Hyperlipidemia and the prevalence of carotid stenosis. CONCLUSIONS: 1. Carotid stenosis is one of the common causes of ischaemic stroke. 2. About 46% of ischaemic stroke patients had carotid stenosis in our study. 3. The prevalence of carotid stenosis increases with increase in age, male gender, smoking, DM, HT & Hyper lipidemia. 4. DM, HT, Smoking & Hyperlipidemia act as risk factors for carotid stenosis. Hence patients with DM, HT & Hyperlipidemias should have their carotid arteries screened to detect asymptomatic carotid stenosis and if present, should have their blood glucose, blood pressure and lipids under control and should be started on antiplatelet drugs and statins for plaque regression and for primary prevention of stroke. 5. Patients with stroke who have carotid stenosis (symptomatic carotid stenosis) are prone for recurrence of stroke. They should be advised to control the risk factors for carotid stenosis and should be started on anti platelet drugs and statins. Carotid endarterectomy should be done in selected cases for secondary prevention of stroke. 6. A simple, non invasive screening procedure like Doppler sonography of the carotid arteries in high risk individuals could therefore have profound diagnostic and therapeutic implications in predicting and preventing a potentially fatal and devastating stroke.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Prevalence ; Carotid Artery Stenosis ; Acute Ischaemic Stroke Patients. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 28 Mar 2018 05:20 |
| Last Modified: | 31 Mar 2018 01:57 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/6683 |
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