Etiological and Metabolic Profile Hypokalemic Periodic Paralysis

Nivas, B (2008) Etiological and Metabolic Profile Hypokalemic Periodic Paralysis. Masters thesis, Madras Medical College, Chennai.


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CONCLUSION: 1. Among the patients with Hypokalemic Periodic Paralysis two thirds of them are due to secondary causes. 2. In our study the common causes are Idiopathic or sporadic periodic paralysis, Gitelman’s/Bartter syndrome and Distal Renal Tubular Acidosis. 3. Measurement of urinary potassium excretion and acid-base parameters provide valuable clues to differentiate between these disorders. 4. The age of onset of Idiopathic or sporadic periodic paralysis is significantly less than due to secondary causes. 5. Idiopathic PP and Gitelman’s syndrome commonly affect males whereas Distal RTA commonly affects females. 6. There is a statistically significant difference in age, age of onset, chloride, 24 hr urinary potassium values when patients with Idiopathic PP, Distal RTA and Gitelman’s syndrome are compared. 7. It is essential to correct hypokalemia before alkali therapy in patients with metabolic acidosis and to correct hypomagnesaemia along with correction of hypokalemia in patients with metabolic alkalosis. 8. Outcome was good in all of our patients.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Etiological ; Metabolic Profile ; Hypokalemic Periodic Paralysis.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 28 Mar 2018 03:59
Last Modified: 30 Mar 2018 17:13

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