Profile and Outcome of Nutritional Anemia in Children attending the Pediatric Department of a Tertiary Care Hospital in Chennai

Indhumathi, A T (2015) Profile and Outcome of Nutritional Anemia in Children attending the Pediatric Department of a Tertiary Care Hospital in Chennai. Masters thesis, ESIC Medical College & Post Graduate Institute of Medical Science and Research, Chennai.

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Abstract

AIM: To study the profileof nutritional anemia in children and to determine the treatment outcome of iron deficiency anemia. METHODS: A total of 150 children with confirmed anemia were enrolled in this study. After a targeted history and clinical examination, hematological investigations were done. Children with microcytic hypochromic anemia were treated with oral iron and followed up after 1 and 3 months for improvement. RESULTS: In the study population, 55 children were found to have microcytic hypochromic, 15 children had normocytic hypochromic and 80 children had normocytic normochromic anemia. Among the microcytic hypochromic group, the mean hemoglobin was found to be 8.22 ± 1.27 g/dL. Symptom analysis revealed 54.5% of children with iron deficiency anemia had lethargy and 34% had irritability. Pica was seen in 47.3% of children with microcytic hypochromic anemia. Hemoglobin levels correlated well with red cell indices, but it was found that 52.7% of children had normal serum ferritin levels. After treatment, it was found that the mean hemoglobin increased from 8.25 ± 1.30g/dLto 9.17 ± 1.36g/dLafter one month and after three months, there was a further increase z 10.39 ± 1.36g/dL. CONCLUSION: In children with iron deficiency anemia, normal or high ferritin level should not distract the physician away from the diagnosis as co-existing infection and inflammation may confound the picture. In cases of normocytic, normochromic anemia, S. ferritin levels can mask a latent iron deficiency.Hence, a therapeutic trial of oral iron is more cost effective.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Children ; Iron Deficiency Anemia ; Red Cell Indices ; Iron Profile ; Treatment Outcome.
Subjects: MEDICAL > Paediatrics
Depositing User: Punitha K
Date Deposited: 23 Mar 2018 07:22
Last Modified: 23 Mar 2018 11:25
URI: http://repository-tnmgrmu.ac.in/id/eprint/6463

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