The Prevalence of Thyroid Dysfunction in Rheumatoid Arthritis

Bincy, B K (2012) The Prevalence of Thyroid Dysfunction in Rheumatoid Arthritis. Masters thesis, Madurai Medical College, Madurai.


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AIMS: The aim of the study was to evaluate the the prevalence of thyroid dysfunction and the incidence of autoimmune thyroditis in rheumatoid arthritis. METHODS: The study was a cross sectional observational study involving 50 rheumatoid arthritis patients (8 male and 32 female). The conditions which can alter thyroid profile were excluded from the study population at the time of selection. 40 age and sex matched healthy subjects were taken as controls. Thyroid function test were done in all patients and controls. In patients who were found to have thyroid dysfunction TPO antibodies were done. RESULTS: Prevalence of thyroid dysfunction is 14% in patients with rheumatoid arthritis. Prevalence of thyroid dysfunction in control population was 5%. Among patients who had thyroid dysfunction there was no statistically significant difference in gender. Abnormal thyroid function is mainly in the form of both overt and subclinical hypothyroidism. Prevalence of autoimmune hypothyroidism is 22% in our case population. CONCLUSION : In summary, our study confirms that the prevalence of thyroid dysfunction in rheumatoid arthritis is high and is associated with thyroid autoimmunity and suggest that all rheumatoid arthritis patients should undergo thyroid function testing and those with elevated TSH should go for autoimmune screening with TPO.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Prevalence ; Thyroid Dysfunction ; Rheumatoid Arthritis.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 20 Mar 2018 01:31
Last Modified: 20 Mar 2018 01:31

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