Nestroft as a screening tool to Identify Beta Thalassaemia Trait in Paediatric Cases.

Santhi, T A (2010) Nestroft as a screening tool to Identify Beta Thalassaemia Trait in Paediatric Cases. Masters thesis, Tirunelveli Medical College, Tirunelveli.


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In India, There Are Around 20 Million Carrier Cases Of -Thalassaemia And Around 8000-10,000 Children Are Born Every Year With -Thalassaemia Major, Lokeshwar M.R. Shah N, Kanakia N. Et.Al 2006. The Birth Of A Thalassaemia Child Places Considerable Health And Economic Strain Not Only On The Affected Child And His/Her Family But Also On The Community. Since, Thalassaemia Is A Severe And Incurable Disease, Emphasis Has To Be Shifted From The Treatment Of An Affected Child To The Prevention Of Such Births In Future. Identifying Carriers For - Thalassaemia Patients, Thus Plays An Important Role In Preventing This, Verma IC Et.Al (1992). - Thalassaemia Trait Presents With Microcytic Hypochromic Blood Picture Similar To The Picture Of Iron Deficiency Anemia And Anemia Of Chronic Diseases. The Differentiation Between These Conditions Becomes Mandatory Which Usually Relies On The Measurement Of Serum Ferritin, Serum Iron, Total Iron Binding Capacity And Hb A2 Levels. These Diagnostic Methods Are Costly And Hence Constitute A Significant Burden On Public Health Economy Particularly In Developing Countries Like India. This Made The Way For Developing A Simple And Economic Screening Test For The Detection Of Carriers Of - Thalassemia. In 1988 Mehta BC Et Al Developed A Simple Cost Effective Screening Test For The Detection Of Cases Of -Thalassemia Trait Based On Reduced Osmotic Fragility. This Is Called NESTROFT (Naked Eye Single Tube Red Cell Osmotic Fragility Test). We Have Tried To Assess The Usefulness Of This Screening Test In Our Paediatric Cases Presenting With Anemia.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Nestroft ; Screening Tool ; Identify Beta ; Thalassaemia Trait ; Paediatric Cases.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 29 Jun 2017 07:34
Last Modified: 29 Jun 2017 07:34

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