A Study on Electrocardiographic and Echocardiographic changes in Chronic Obstructive Airways Disease

Murugesan, V (2009) A Study on Electrocardiographic and Echocardiographic changes in Chronic Obstructive Airways Disease. Masters thesis, Kilpauk Medical College, Chennai.


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INTRODUCTION: Chronic Obstructive Airways Disease is acknowledged by the “WHO” as the fourth commonest cause of death worldwide. It is projected to be the third most common cause of death and fifth most common cause of chronic disability by the year 2020. Earlier in the 20th century TB was the major pulmonary disease in developing countries. Its place has been taken by two diseases in the later half of 20th century namely chronic obstructive airways disease and Carcinoma of lung. Cigarette smoking is said to have been playing a major role in the etiology of Chronic Obstructive Airways Disease. Knowing the ill effects of smoking many governments including Indian Government have banned smoking in public places. This may in future lead to reduction in number of smokers and its ill effects thus reducing the incidence of COAD in due course. Chronic Obstructive Airways Disease is known to cause airflow limitations, impaired gas exchange and increased pulmonary artery pressure. According to literatures prevalence of pulmonary hypertension in chronic obstructive airways disease is 18%1. Elevated pulmonary artery pressure is a predictor of mortality in chronic obstructive airways disease. “Weitzenblum” and coworkers2 showed a 72% 4 year survival in patients with normal pulmonary artery pressure compared with 49% survival in patients with an elevated pulmonary artery pressure in Chronic Obstructive Airways Disease. Both electrocardiography and echocardiography are very useful in the detection of elevated pulmonary artery pressure. Here an attempt has been made to correlate clinical features, pulmonary function tests, electrocardiography and echocardiography in case of Chronic Obstructive Airways Disease patients. AIM OF THE STUDY: To analyze various cardiovascular manifestations of “Chronic Obstructive Airways Disease” with the help of Electrocardiography and Echocardiography. MATERIALS AND METHODOLOGY: Population: Patients attending the out patient clinic &who were admitted in “Government Royapettah Hospital, Chennai” with complaints of persistent cough with expectoration for 3 months in two consecutive years or who have cough, breathlessness with clinical or x-ray evidence of hyper inflation were selected for the study (50 patients). Period of the study: January 2008 –July 2008. Inclusion criteria: Patients with spirometric evidence of chronic obstructive airways disease. Criteria for diagnosis of chronic obstructive airways disease - FEV1<80% predicted value & FEV1/FVC < 70%. Exclusion criteria: Patients with TB, bronchial asthma, bronchiectasis, bronchogenic carcinoma, interstitial lung disease, coronary artery heart disease, systemic hypertension, aortic & mitral valve disease, right heart failure& patients residing at high altitude were excluded from the study by doing x-ray chest, Mantoux test, sputum for acid fast bacilli & blood pressure measurement. CONCLUSION: In my study Chronic obstructive airways disease is more common in males. • Smoking is the principle cause of Chronic obstructive airways disease. • Severity of Chronic obstructive airways disease is directly proportional to intensity of smoking. • Severity of Chronic obstructive airways disease is associated with earlier age of onset of smoking especially in teen ages. • Most patients are in low socioeconomic status. • Electrocardiography has high sensitivity in detecting pulmonary hypertension in Chronic obstructive airways diseased patients as evidenced by P pulmonale, right axis deviation, right ventricular hypertrophy. Majority of the patients with electrocardiographic evidence of pulmonary hypertension also had Echocardiographic evidence of elevated pulmonary artery pressure. So both Electrocardiography and Echocardiography are very useful in the assessment of severity of chronic obstructive airways disease.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Chronic Obstructive Airways Disease ; Electrocardiographic changes ; Echocardiographic changes.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 11 Mar 2018 04:17
Last Modified: 11 Mar 2018 04:17
URI: http://repository-tnmgrmu.ac.in/id/eprint/6130

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