Cytological Grading of Ductal Carcinoma of Breast in Fine Needle Aspirates and its Correlation with Histological Grading.

Hidhaya Fathima, K (2013) Cytological Grading of Ductal Carcinoma of Breast in Fine Needle Aspirates and its Correlation with Histological Grading. Masters thesis, Coimbatore Medical College, Coimbatore.

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Abstract

Breast Cancer Is The Second Most Common Cancer In Females World Wide Accounting For About 1.4 Million Cases Each Year, With More Than Half Of The Deaths Due To Breast Cancer Occurring In Low And Middle Income Countries. Breast Cancer Is The Second Leading Cause Of Cancer Related Deaths In Females All Over The World66. Breast Cancer Have Doubled In India In The Last Two Decades. The Number Of Women Estimated To Be Dying Of Breast Cancer Every Year Has Also Been Steadily Raising. As Against An Estimated 48,170 Women Who Died Of Breast Cancer In 2007, The Number Reached The 50,000 In 2010,Which Raised To 50,821 By 2011.An ICMR Study In Many Cosmopolitan Cities Like Chennai Revealed That The Incidence Of Cervical Cancer Had Been Dropped And Breast Cancer Incidence Were Emerging. Between 2006-2008 The Incidence Of Breast Cancer In Chennai Was 26.5%(ICMR).As Per Study Conducted In Coimbatore, Percentage Of Occurrence Of Breast Cancer Was Found To Be 20.3out Of 1 Lakh Women. Fine Needle Aspiration Cytology Is Being Increasingly Used To Determine The Benign And Malignant Nature Of The Lesion. This Also Provides Additional Information About The Intrinsic Nature Of The Lesion And The Prognosis12.Attempts Have Been Made To Determine Various Prognostic Parameters On FNA Material To Determine The Best Therapy In A Given Case 68,69. Due To Its Tremendous Increase In Incidence Rates, It Is Desirable To Grade The Tumor While Is Still In Vivo For The Selection Of Appropriate Therapy And To Avoid Overtreatment For Low Grade Carcinoma. The Significance Of Histological Grading Was Accepted .It Was Also Found To Be A Useful Supplementary Prognostic Parameter .So When A Significant Association Was Established Between Cytologic And Histologic Grading Systems, Cytologic Grading May Be Helpful To Decide The Level Of Treatment.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Cytological Grading ; Ductal Carcinoma ; Breast Fine Needle Aspirates ; Correlation. Histological Grading;
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 29 Jun 2017 07:20
Last Modified: 14 Jul 2017 06:26
URI: http://repository-tnmgrmu.ac.in/id/eprint/607

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