Study of Serum Magnesium Level in Type 2 Diabetes Mellitus

Subash Chandra Bose, G (2013) Study of Serum Magnesium Level in Type 2 Diabetes Mellitus. Masters thesis, Thanjavur Medical College, Thanjavur.


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BACKGROUND : A high prevalence of magnesium deficiency is reported in diabetics. Magnesium depletion has a negative impact on glucose homeostasis and insulin sensitivity in type 2 diabetic patients as well as on the evolution of complications such as retinopathy, nephropathy, neuropathy and arterial atherosclerosis. The aim of this study is to estimate the prevalence of hypomagnesemia in patients with type 2 diabetes mellitus and its correlations with microvascular complications of diabetes like retinopathy, nephropathy, neuropathy. MATERIALS AND METHODS : Patients with type 2 diabetes admitted in Thanjavur Medical College and Hospital over a period of one year between October 2011 to October 2012 formed the study population. The sample size was 100 patients. Serum magnesium concentration was measured by calmagite dye method. RESULTS : The study revealed that prevalence of hypomagnesemia in study subjects was 35%. Sex, age and duration of diabetes were not significant predictors of serum magnesium. Significant association was found between hypomagnesemia and diabetic retinopathy, nephropathy, neuropathy. Significant correlations were not found with co morbidities such as ischemic heart disease and hypertension. Low serum magnesium concentrations are common in type 2 diabetics. Magnesium deficiency is conclusively associated with diabetic retinopathy, nephropathy, neuropathy.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Magnesium ; Diabetes Mellitus ; Retinopathy ; Nephropathy ; Neuropathy.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 06 Mar 2018 07:11
Last Modified: 06 Mar 2018 07:11

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