Lalith Narayan, B (2013) A Study of Voluntary Kidney Donors: Post Transplant. Masters thesis, Thanjavur Medical College, Thanjavur.
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Abstract
BACKGROUND AND OBJECTIVE : The incidence and prevalence of chronic kidney disease is increasing in India. CKD stage V is reached earlier in life. Renal transplantation is the best choice of treatment for CKD stage V. Living donor kidney transplantation represents about 95% of renal transplantations in India. Uninephrectomy for kidney donation puts the donor at risk for renal failure and the development of glomerular hyper-filtration syndrome. Studies from the West have have documented the safety of living kidney donation. There are limited numbers of studies from India regarding kidney donors. MATERIALS AND METHODS : The voluntary kidney donors of 50 transplant recipients attending the Department of Nephrology-Transplant OPD were chosen and enrolled in the study after informed consent. The donors had a post nephrectomy period ranging from <1 year to 27 years. They were screened for hypertension, proteinuria and renal failure. Their attitude toward kidney donation was studied. RESULTS : 39 female donors and 11 male donors were enrolled. Wives were the single major group of donors. The mean age of the donors studied was 49 years, with a mean post donation period of 6.58 years. Female donors had a mean age at donation less than the males. The mean systolic blood pressure was 122.32±13.65 mmHG and mean diastolic blood pressure was 79.16±9.85 mmHg. The prevalence of hypertension among the donors was similar to the population based studies. None of the donors had proteinuria. Only one donor had elevation of urea and creatinine. The mean time taken by the donors to return to normal life was 4.08 weeks. All the donors had a positive attitude towards donation. CONCLUSION : The donors seem to have no additional prevalence of hypertension as compared to the general population. No proteinuria or major deterioration in renal function was noted. All the donors had a positive attitude towards kidney donation. Living kidney donation appears to be safe in the Indian scenario also. Larger prospective studies are needed to confirm this.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Kidney donors ; living kidney donation ; glomerular hyperfiltration ; renal transplantation. |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 06 Mar 2018 06:34 |
| Last Modified: | 06 Mar 2018 06:34 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/6052 |
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