Placental Pathology in Low Birth Weight Live Births.

Yogalakshmi, S (2012) Placental Pathology in Low Birth Weight Live Births. Masters thesis, Coimbatore Medical College, Coimbatore.


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Aim : To study the various pathological changes (both gross and histological) that occur in the placentas of low birth weight live births. Objectives : To study the gross morphological and histological appearance of placentas of low birth weight live births and to derive a probable etiology for low birth weight, based on placental pathology. Materials and methods- It is a Prospective Study from September 2009 to September 2011 carried out in Coimbatore Medical College and Hospital. 50 placentas expelled during normal delivery or caesarean section were subjected to pathological examination. Detailed history of the mother was recorded and results were analyzed. Results : Pregnancy induced hypertension and anemia are the most common conditions that produce low placental weights and low birth weight (LBW) live births. Placental morphological changes increase in direct proportion to the severity of diseases. Membrane opacities (48%), perivillous fibrin deposit (46%) and placental infarcts are the most commonly observed gross morphological changes. Syncytial knots (88%) and fibrinoid necrosis (88%) are the most common histological finding. Increased syncytial knot formation is a consistent feature of anemia and Pregnancy induced hypertension and increased basement membrane thickness is a common finding in severe anemia.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Syncytial knots ; fibrinoid necrosis ; perivillous fibrin deposit ; placental infarct.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 29 Jun 2017 02:48
Last Modified: 29 Jun 2017 02:48

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