Inter-Ictal Psychosis of Epilepsy: Clinical Profile and Predictive Variables

Priya, R (2008) Inter-Ictal Psychosis of Epilepsy: Clinical Profile and Predictive Variables. Masters thesis, Madras Medical College, Chennai.


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Psychosis is widely accepted as a complication of epilepsy. With regard to phenomenology, etiology and prognosis both psychosis and epilepsy are complex disorders. Studying their association is therefore challenging. Some aspects of this association are now better established than they were at the time of Slater’s classic report on psychosis of epilepsy. Over the past four decades a consensus has begun to take shape that certain forms of epilepsy may act as risk factors for subsequent development of chronic interictal psychosis, a syndrome sometimes referred to as the schizophrenia-like psychosis of epilepsy. This psychosis does resemble schizophrenia in its phenomenological manifestations, pursues a similar course and is responsive to antipsychotic medications. Considering that epilepsy may be a risk factor for development of psychosis, it is important to identify if there are epileptic characteristics that predict such a development. This study is to analyse the association of interictal psychosis and epilepsy and to identify the predictive variables for interictal psychosis in epilepsy. The most important predictors for development of interictal psychosis associated with epilepsy were Earlier age of onset of epilepsy, Chronic long standing epilepsy, Increased frequency of seizures, Complex partial seizures, Psychosis was most often schizophrenic in nature with thought disturbances, auditory and visual hallucinations.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Inter-Ictal Psychosis ; Epilepsy ; Predictive Variables ; Clinical Profile.
Subjects: MEDICAL > Neurology
Depositing User: Kambaraman B
Date Deposited: 28 Jun 2017 10:53
Last Modified: 22 Dec 2018 09:31

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