Radhika, Gopal (2017) The Efficacy of Aerobic Exercise and Relaxation Technique in Fatigue among Children with Acute Lymphoblastic Leukemia: A Comparative study. Masters thesis, College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore.
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Abstract
INTRODUCTION : Childhood cancer is one of the leading cause of death by disease among which Acute Lymphoblastic Leukemia (ALL) accounts for 30% of all the malignancies. ALL is the most common form of pediatric leukemia which is also known as Acute Lymphocytic or Acute Lymphoid Leukemia. Incidence is approximately 3-4 cases per 100,000 children below 15 years with peak incidence below 2-5 years of age. In most of the countries, the incidence rate in children was approximately four times than that of the adults. Studies have shown a 98% cure rate in ALL. But even with these survival rates in pediatric population, only half of the ALL patients survived 5 years. Exact etiology of ALL is still unknown but common etiological factors include ionizing radiations, congenital anomalies, chemical agents like Benzene and Immunodeficiency syndromes. Many studies have reported the risk factors like Down syndrome, Erbstien Barr Virus (EBV) infections, parental history of fetal loss, miscarriage, perinatal exposure to pesticides and still birth to be reasons for developing leukemia. The pathogenesis of ALL is assumed to be the neoplasm arising from the clonal proliferation of immature cells of hemopoetic system which are characterized by the aberrant or arrested differentiation. The associated complications of ALL include musculoskeletal, Central Nervous System (CNS) and other systemic complications. Recent study have shown that 2% of the boys diagnosed with ALL shows testicular enlargement. Neural complications like pain, paresthesia and reduced deep tendon reflexes have been reported in various studies. Musculoskeletal complications like impaired gross motor and fine motor performances, increased fatigue, compromised ROM, strength and endurance have also been identified. Unfortunately, fatigue has become the most debilitating symptom in patients with cancer. It was reported to be an intensive disability among cancer patients as it induces inactivity which on prolonged rest lead to muscle wasting and loss of endurance. Fatigue affects quality of life to about 60% in cancer patients. But limited focus was given to those groups recognized with fatigue complaining unique experiences. AIM OF THE STUDY : This study was aimed to find out the effect of aerobic training and relaxation technique on fatigue in children with ALL. OBJECTIVES : 1. To find out the effectiveness of CSF in aerobic training among children with ALL. 2. To find out the effectiveness of PSF in aerobic training among children with ALL. 3. To find out the effectiveness of CSF in relaxation technique among children with ALL. 4. To find out the effectiveness of PSF in relaxation technique among children with ALL. 5. To compare the outcomes of CSF between the aerobic training and relaxation technique among children with ALL. 6. To compare the outcomes of PSF between the aerobic training and relaxation technique among children with ALL. METHODOLOGY : Study Design : A comparative study. Study Setting : Pediatric inpatient oncology ward, Sri Ramakrishna Institute of Oncology and Research, Coimbatore. Sampling Technique : A convenience sampling. Sample Size : A total of 30 acute lymphoblastic leukemia patients was selected on the basis of inclusion criteria and conveniently allocated into two groups of 15 each. Both the groups were designed for experimentation. Study Duration : The study was conducted over a period of 10 months. Treatment Duration : The treatment duration was 4 weeks. Inclusion Criteria : • Children undergoing chemotherapy. • Aged between 5-12. • Both gender. • Children with preserved cardiac function. • Children able to accept and follow verbal instructions. • Children complaining of fatigue. Exclusion Criteria : • Children with unstable cardiac function. • Children with platelet count less than 3000/uL. • Children with recent surgeries(less than 3 months). • Children with congenital musculoskeletal anomalies. • Children with visual and hearing deficits. • Children with systemic complications. RESULTS : The mean values of aerobic training group (27.7) is greater than the relaxation training group (23.3). The calculated ‘t’ value is 2.848 which is greater than the table value (2.048). The study showed that there is significant difference in child fatigue scale level of aerobic training group and relaxation training group at the level of p<0.05. This shows that aerobic training is effective than the relaxation training in improvement of fatigue among ALL children. CONCLUSION : The study confirmed the effects of both Aerobic exercise and Relaxation technique which could reduce the level of fatigue among children with ALL. The aerobic training yield better results compared to relaxation training in reducing fatigue level among ALL children.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Aerobic Exercise, Relaxation Technique, Fatigue, Children, Acute Lymphoblastic Leukemia. |
| Subjects: | PHYSIOTHERAPY > Physiotherapy in Paediatrics |
| Depositing User: | Kambaraman B |
| Date Deposited: | 01 Feb 2018 15:39 |
| Last Modified: | 01 Feb 2018 15:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/5591 |
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