Natarajan, L (2007) Estimation of Plasma Antioxidants – Vitamin E and Vitamin C in Oral Pre-Cancer and Cancer Patients. Masters thesis, Meenakshi Ammal Dental College, Chennai.
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Abstract
1. This study comprised of 75 cases that included apparently normal individuals with no history of tobacco habits or clinical evidence of oral lesions, patients with history of tobacco related habits but without clinical evidence of oral lesions, patients having tobacco related habits with oral pre cancerous lesions and conditions (Leukoplakia, oral sub mucous fibrosis), patients having tobacco related habits with established oral carcinoma. 2. Plasma levels of Vitamin-E and Vitamin-C were estimated by Spectrophotometeric analysis in these patients. 3. We observed that the values of Vitamin-E were not significant statistically between normal controls and different study groups as well as within the study groups. 4. We observed that the values of Vitamin-C were statistically significant between normal controls and different study groups as well as within the study groups. 5. Comparison of Vitamin-E and Vitamin-C level shows statistically significant gradual reduction of Vitamin C level between patients with tobacco habits without lesions(group B), Individuals with tobacco related habits with precancer(group-C), individuals with tobacco related habits with oral cancer(group-D) compared to controls ; however, Vitamin E level does not show significant variation between these groups. 6. Comparison of our results with other research workers, we concur that Vitamin-C has sparing effect on Vitamin-E as it is considered to regenerate Vitamin-E from tocopheroxyl radical after it has neutralized free radicals.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Plasma Antioxidants, Vitamin E, Vitamin C, Oral Pre-Cancer, Cancer Patients. |
| Subjects: | DENTAL > Oral Pathology and Microbiology |
| Depositing User: | Kambaraman B |
| Date Deposited: | 24 Jan 2018 03:53 |
| Last Modified: | 24 Jan 2018 03:53 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/5540 |
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