A Comparative Cytomorphometric study of the buccal mucosa in Tobacco users (Smoking, Chewing and Combined habits) and non-users

Balasubramanian, L (2005) A Comparative Cytomorphometric study of the buccal mucosa in Tobacco users (Smoking, Chewing and Combined habits) and non-users. Masters thesis, Tamil Nadu Government Dental College and Hospital, Chennai.

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Abstract

This study was done to assess the cell diameter (CD) and nuclear diameter (ND) of squames in clinically normal buccal mucosa of patients having tobacco habits and to correlate with gender and age. The cell and nuclear size of normal subjects showed wide variation. ND ranged from 7.8 μ to 8.5μ and CD ranged from 46.20μ to 72.61μ. The mean cell diameter in the tobacco non-user group (51.ur ± 1.36) is significantly higher than the various tobacco user groups. The mean cell diameter of tobacco smokers, chewers and combined habit groups are 50.80 ± 0.70, 50.81 ± 1.12 and 50.47 ± 0.89 respectively. Though the mean cell diameter slightly decreased from tobacco smoker to chewer to combined habit group. The mean nuclear diameter in the tobacco non-user group (8.42 ± 0.21) is significantly lower than the various tobacco user groups. The mean nuclear diameter of tobacco smokers, chewers and combined habit groups are 8.80 ± 0.25, 8.85 ± 0.26 and 8.88 ± 0.32 respectively. The mean nuclear diameter slightly increased from the tobacco smoker to chewer to combined habit group. The reduction in the cell diameter and an increase in the nuclear diameter in the tobacco user groups show that these parameters could be early indications towards dysplasitc changes. Comparison of cell diameter (CD) and nuclear diameter (ND) between males and females in different study groups showed no significant difference by students independent t – test. Comparison of cell diameter (CD) and nuclear diameter (ND) between no habit group and tobacco user groups showed significant difference. No significant difference was seen in the cell diameter (CD) and nuclear diameter (CD) between the different tobacco user groups in the study by one-way ANOVA and multiple Range test by Tukey HSD procedure. Comparison of cell diameter (CD) and nuclear diameter (ND) between different age groups (<30,31-40, 41-50, >51 years) by oneway ANOVA and multiple range test by Tukey HSD procedure showed no significant difference. This prelimnary study shows that various tobacco habits have significant alteration in the mean cell diameter and mean nuclear diameter of squames of buccal mucosa.

Item Type: Thesis (Masters)
Uncontrolled Keywords: buccal mucosa, tobacco users, Smoking, Chewing, Combined habits, non-users.
Subjects: DENTAL > Oral Pathology and Microbiology
Depositing User: Kambaraman B
Date Deposited: 24 Jan 2018 03:53
Last Modified: 24 Jan 2018 03:53
URI: http://repository-tnmgrmu.ac.in/id/eprint/5531

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