A Study of Ischemic Stroke in Young.

Gunasekaran, A (2007) A Study of Ischemic Stroke in Young. Masters thesis, Madras Medical College, Chennai.


Download (254kB) | Preview


The World Health Organisation defines the Stroke as “rapidly developing clinical signs of focal disturbance of cerebral function, with symptoms lasting for 24 hours or longer or leading to death, with no apparent cause other than of vascular origin". The National Institute of Neurological Disorders and Stroke (NINDS) applies the term “ Stroke “ to any one or all of a group of disorders including cerebral infarction, intracerebral hemorrhage or subarachnoid hemorrhage. Age is the most powerful predictor of the stroke .The incidence of the stroke increases exponentially with the age. It is now well known that stroke in young adults is not a rare event. Although the frequency of stroke is lower than in general population, stroke is particularly dramatic in younger patients because it involves a previously healthy adult and the burden is extremely heavy on the spouse and the family. Stroke in young patients constitutes a challenge because of its social impact and also because of the large variety of associated diagnostic and therapeutic problems. The causes of stroke are more heterogenous than in older population. Cardiac disease, hematological disease, nonatherosclerotic arteriopathies, migraine and drug abuse are more important causes for stroke in young adults than in adults. The differential diagnosis includes many genetic, congenital, metabolic and systemic disorders that are rarely encountered in mature adult populations. Brain and vascular location of lesions are somewhat different in the young .Cerebral infarcts tend to be more often limited to deep regions of cerebral hemispheres , especially striatocapsular region. Vascular occlusive lesions are more often intracranial, affecting especially supraclinoid internal carotid artery , proximal middle cerebral artery and basilar artery. Extracranial occlusive disease is much less common. The ischemic strokes among young patients were caused by a broad spectrum of diseases. All young patients with stroke deserve detailed evaluation to determine the etiology. Aggressive evaluation leads to etiological diagnosis and so proper acute management as well as long term care. When the cause of ischemic stroke in a young adult is unclear after a thorough initial diagnostic evaluation, it is worthwhile to take a second look at the heart. Investigations should be tailored to suit the need of the particular case rather than a complete list of tests for all patients.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Ischemic Stroke ; Young.
Subjects: MEDICAL > Neurology
Depositing User: Kambaraman B
Date Deposited: 28 Jun 2017 10:03
Last Modified: 28 Jun 2017 10:03
URI: http://repository-tnmgrmu.ac.in/id/eprint/550

Actions (login required)

View Item View Item