A Study on Acute Kidney Injury in Postoperative Patients at Government Stanley Hospital, Chennai

Manikandan, V (2015) A Study on Acute Kidney Injury in Postoperative Patients at Government Stanley Hospital, Chennai. Masters thesis, Stanley Medical College, Chennai.

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Abstract

OBJECTIVE: 1. To assess the risk factors causing AKI in post operative patients. 2. To assess the incidence of AKI in post operative patients. METHODOLOGY: Patients in postoperative period with acute kidney injury in Stanley Medical College Hospital, during the period of february to september 2014 fulfilling the inclusion and exclusion criteria were included in the study and 60 patients had AKI fulfilling the criteria. Stastical analysis were done using EpiInfo software (7.1.0.6 version; Center for disease control, USA) and Microsoft Excel 2010. Continuous variables were analysed with Unpaired t test and categorical variables were analysed with the Chi-Square Test and Fisher Exact Test. Statistical significance was taken as P < 0.05. RESULTS: The study was a prospective study and 60 patients had AKI during the time period in postoperative period. The incidence of AKI was 1.48%. Intraoperative hypotension was found to be a significant risk factor. CONCLUSION: 1. The risk of developing AKI in patients undergoing surgery were evaluated over a period of 6 months. 2. It was found that patients undergoing cardiac surgery were found to have high risk followed by vascular and other surgeries. 3. The incidence of AKI is 1.48%. 4. When patients were classified according to AKIN criteria of >0.3 mg/dl rise of creatinine all the above patients were found to have AKI, but when classified according to RIFLE criteria of >50% rise around 31 patients were found to have AKI. 5. From this study patients undergoing cardiac surgery were found to be at higher risk, and intra operative hypotension was a significant risk factor. 6. The serum creatinine is not a true and early marker of acute kidney injury and there is delayed rise. 7. Most of the patients recovered from AKI after 7 days of surgery.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Acute Kidney Inury ; Glomerular Filtration Rate ; Cardiac Surgery ; Rifle Criteria.
Subjects: MEDICAL > General Medicine
Depositing User: Punitha K
Date Deposited: 17 Jan 2018 06:05
Last Modified: 11 May 2018 15:14
URI: http://repository-tnmgrmu.ac.in/id/eprint/5473

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