A study on Red Blood Cell count, Distribution Width and Neutrophil/ Lymphocyte Ratio as Markers of Vascular Inflammation in the Early Detection of Non Proliferative Diabetic Retinopathy.

Boopathi Rajan, P (2015) A study on Red Blood Cell count, Distribution Width and Neutrophil/ Lymphocyte Ratio as Markers of Vascular Inflammation in the Early Detection of Non Proliferative Diabetic Retinopathy. Masters thesis, Stanley Medical College, Chennai.

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Abstract

About 100 Type-II Diabetic patients with / without visual symptoms attending Ophthalmology and diabetology OPDs after satisfying the Inclusion/ Exclusion Criteria will be included in the study. All patients will be subjected to symptom analysis, clinical examination and laboratory investigation. Final results will be analyzed by SPSS statistical software. RESULTS Our study was a Cross-sectional study conducted among 100 Type-II diabetic patients between 30-50 years of age. Two group were assigned according to the severity of Diabetic Retinopathy. One is a mild grade and another is a moderate grade. NLR, RDW and RBC count were analyzed in this study population. Also HBAIC and blood glucose levels were correlated with them. Statistical analysis was done with SPSS Software. Results were studied using unpaired t-test, chi-square test and Pearson coefficient Correlation. 2 CONCLUSION From our study we conclude that, both NLR and RDW are useful markers of vascular inflammation for 1) Early diagnosis of Non-proliferative diabetic retinopathy. 2) Assessing the severity of non proliferative Diabetic Retinopathy as mild or moderate grades. 3) Also their prediction of uncontrolled glycaemic status since they correlate well with HBA1C and blood glucose levels.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Red Blood Cell; Vascular Inflammation; Diabetic Retinopathy
Subjects: MEDICAL > General Medicine
Depositing User: Punitha K
Date Deposited: 03 Jan 2018 11:26
Last Modified: 03 Jan 2018 11:26
URI: http://repository-tnmgrmu.ac.in/id/eprint/5180

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