Pious, K (2012) Clinical features, fundus fluorescein angiography findings, optical coherence tomography findings and visual outcome after treatment with intravitreal bevacizumab in parafoveal telangiectasis. Masters thesis, Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli.
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Abstract
AIM: To evaluate the clinical features, fundus fluorescein angiographic (FFA), optical coherence tomographic (OCT) findings and to study the effect of intravitreal bevacizumab in type 2 parafoveal telangiectasia (PFT). PATIENTS AND METHODS: In this prospective, interventional case series, patients with clinical diagnosis of PFT were divided into 3 groups: eyes with PFT alone (group 1), eyes with PFT with cystoid macular edema (CME) (group 2) and eyes with PFT with Choroidal neovascular membrane (CNVM) (group 3). Eyes with PFT with CME and CNVM received intravitreal bevacizumab (2.5mg/0.1ml). Main outcome measures studied were reduction in macular thickness and improvement in visual acuity. RESULTS: Eighty eyes of forty patients (14 males and 26 females), ranging in age from 40 to 70 were included in the study. Eyes with PFT alone showed no change in visual acuity or macular thickness during follow up. Eyes with PFT with CME showed improvement in visual acuity (p<0.001) and in macular thickness (p<0.001). Eyes with PFT with CNVM showed improvement in macular thickness after bevacizumab (p<0.001) but not in visual acuity. CONCLUSION: Intravitreal bevacizumab is effective in management of eyes with PFT with CME. In eyes with PFT with CNV, there may be not be improvement in vision after bevacizumab despite reduction in macular thickness.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | fundus fluorescein angiography; optical coherence tomography; visual outcome; intravitreal bevacizumab; parafoveal telangiectasis |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Devi S |
| Date Deposited: | 02 Jan 2018 11:17 |
| Last Modified: | 02 Jan 2018 11:17 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/5096 |
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