Elamathi, L (2016) A Clinical Evaluation of Elisevi Kudineer a Siddha Drug in the treatment of Keerinoi (Thread Worm - Enterobius Vermicularis) in Children. Masters thesis, National Institute of Siddha, Chennai.
|
Text
320418316elamathi.pdf Download (7MB) | Preview |
Abstract
Worm infestation is one of the common cause of suffering by human being. Small children are particularly prone because they play in the mud and dirt, suck their fingers, eat soil, run barefoot outdoors and some times have less than ideal toilet hygiene. Impure water, low socio-economic state, poor sanitation coupled with low literacy rates of parents particularly, the mothers, are the main causes of this prevalent malady. Lack of knowledge on hygiene and malnutrition in general public has contributed largely to the factors for Nonachievement of ‘health for All by 2000 AD”. Eventhough under five mortality has come down to 93, morbidity is on raise mainly due to malnutrition which is the major cause for under 5 mortality. Malnutrition under 5 under are mainly because of the cause worm infestation Medicine in the prehistoric times was intermingled with superstition, religion, magic and witch craft. Hygiene was given an important place in ancient Indian medicine. The history of herbal medicine is almost as old as human civilization.The plants are known to provide a rich source of botanical anthelmintics, antibacterials and insecticides Anthelmintic that are obtained from the natural resources may play an important role in the treatment of worm infestation with less side effects.Ideally an anthelmintic agent should have broad spectrum of action , high percentage of cure with a single therapeutic dose , free from toxicity to the host and should be cost effective , none of the synthetic drug meets the requirement. Even the most common drugs may results in nausea, intestinal disturbances and giddiness , resistance of the parasite to existing drug and their high cost warrants the search for newer anthelmintic molecules. The drug Elisevi kudineer indicated for Keeri Noi, which may satisfy the drug need to treat the children safely and worth in fulfilling the requirements of anthelmintics . The clinical trial of the drug has not been done so far. So the study may help to step one stone up in the journey of Siddha treatment in children. AIM : To Evaluate the efficacy of ELISEVI KUDINEER for the management of KEERINOI (Thread worm- Enterobius vermicularis) PRIMARY OBJECTIVE : To study the recurrence rate of the disease after giving the trial drug. SECONDARY OBJECTIVES : To review the literature of the disease Keerinoi in Siddha and Modern aspect. To compare the aetiology, incidence, clinical features, treatment, prognosis and complications of Keerinoi with Thread worm (Enterobius vermicularis) in Modern Science. To know the predominance of disease age, sex, climate, immunization history and socio economic status are considered. To Study the Keerinoi on the basis of siddha parameters such as deranged mukkuttram, poripulangal, ezhu udalkattukal and envagai thervugal. To study the pharmacological activity, physico chemical analysis ,and chemical analysis of the trial drug. CONCLUSION : The Siddha system of medicines has certainity with safer medications to treat children. In the present study, the trial drug Elisevi kudineer is treated to the children of age group, 8 12 years who are all diagnosed to have Keeri Noi The ingredients of Elisevi kudineer are feasible and useful; These compounds may serve as potentially useful drug at a lower cost. The medicine has many properties to control the signs and symptoms of Keeri Noi. During the course of treatment, no adverse interactions were observed. Clinical improvement has been noted and analysed statistically which implies the trial drug has very significant result 84% and the lab investigation shows 72.5% cases with good results. The present clinical study has established that Elisevi kudineer is having good result in reducing the majority of symptoms of the Keeri noi and in expeling Keeri Poochi. Further studies are required to establish its mechanism of action. By encouraging result of above study the drug may be taken for larger study in treatment of Keeri Noi.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | (Reg.No.321314202) |
| Uncontrolled Keywords: | Elisevi Kudineer ; Siddha Drug Treatment ; Keerinoi Thread Worm ; Enterobius Vermicularis ; Children ; Clinical Evaluation. |
| Subjects: | AYUSH > Kuzhanthai Maruthuvam |
| Depositing User: | Subramani R |
| Date Deposited: | 28 Jun 2017 02:23 |
| Last Modified: | 17 Dec 2018 18:34 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/486 |
Actions (login required)
 |
View Item |
