Sugavaneshwari, M (2016) A Study on Lasunathabitham. Masters thesis, Government Siddha Medical College, Palayamkottai.
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Abstract
AIM AND OBJECTIVE: AIM:-The principle aim of the present study is to evaluate the efficacy of the trail drug LASUNATHABITHA KUDINEER in the treatment of LASUNATHABITHAM. OBJECTIVES: 1. The main objective of the present study is to create awareness about the siddha system and to highlight the efficacy of Siddha drug among the public people. 2. To study the Casue, clinical Features, diagnosis and investigation of lasunathabitham through various siddha literatures. 3. To figure out the biochemical and pharmacological activites of the drug. 4. To make the correspondent study of the siddha and modern aspect of the disease. 5. To study the pre- clinical analytical standardization and safety study in the experimental formulation of lasunathabitha kudineer. 6. To flash the solitary diagnostic procedure mentioned in Siddha literature of the disease lasunathabitham. 7. To oversight the clinical trial and to final out the efficacy of Lasunathabitha kudineer for the cure of the disease Lasunathabitham. MATERIALS AND METHODS: CLINICAL STUDIES: After finishing the studies 40 cases were selected from the OPD and IPD of Kuzhanthai Maruthuram Department, They were treated with the trail drug Lasunthabitha kudineer and observed for prognosis clinically. STUDY DESIGN AND CONDUCT OF THE STUDY: Study Type : An observational clinical study. Study Place : Post graduate Kuzhanthai Maruthuvam OPD and IPD Government Sidhha Medical College and Hospital Palayamkottai. Study Peroid : 24 months. Sample Size : 40 Patients ( 20 Op + 20 IP). The sample consists all patients 3-12 years age group fulfilling all the inclusion and exclusion criteria. STUDY PARTICIPANTS: INCLUSION CRITERIA: 1. Age 5 to 12 years. 2. Sex - Male and female children. 3. Throat pain. 4. Dysphagia. 5. Hoarseness of voice. 6. Enlarged tonsils. 7. Reffered pain the Ear. 8. Malaise. 9. Mild fever with tonsillitis. EXCLUSION CTITERIA: 1. Congenital anomalies of pharynx. 2. Known case of pulmonary Tuberculosis. 3. Physilogical hyperplasia of lymphoid Follicles. 4. Malignancy. 5. Tonsilitis which have indication for surgery. WITHDRAWAL CRITERIA: 1. The drug not responding to the condition. 2. Intolerance to the drug and development of adverse. reactions during drug trail. 3. Patient turned unwilling to continue in the course of clinical trail. 4. Occurrence of any serious illness. TERMINATION CRITERIA: 1. Not reporting subsequently. 2. Voluntary termination. SUMMARY: The aim of this dissertation subject is to assess the efficacy of trial drug “Lasunathabitha Kudineer” for “Lasunathabitham” without any adverse effects. • Sufficient literatures with reference to Lasunathabitham was not found in siddha system. Hence from the available texts, signs, symptoms and characteristic features were collected and the medicine was chosen for the study. • The Etiopathogenesis and symptoms of Lasunathbitham have been correlated with that of Tonsillitis with evidence of literature. • Clinical diagnosis and selection of cases was based on clinical features described in Pillaipini Maruthuvam text book. • Laboratory diagnosis was done by modern methods of examination. • 20 cases were selected and treated in IPD. Department of Kuzhanthai Maruthuvam, Govt siddha medical college, Palayamkottai for the clinical study. • The medicine choosen for treatment and management of Lasunathabitham was Lasunathabitha Kudineer (10 – 30ml) internally, twice a day. • The trial drug selection is based on its siddha pathological and pharmacological action to rectify the deranged Mukuttram and also due to its antiinflammatory, antihistamine effect of ingredients. • All the children were kept under strict dietary control during the treatment. The observation on effect of therapy was encouraging. • The documentation of observation made during the clinical study showed that the drug is clinically effective. • The Biochemical analysis of the trial drug had ferrous iron which adds to the clinical prognosis of Lasunathabitham by Lasunathabitha Kudineer. • Anti bacterial activity of Lasunathabitha Kudineer showed that it inhibited the growth of bacterial strain against streptococci and staphylococci. • In pharmacological analysis, the trial medicine Lasunathabitha kudineer had siginificant Anti – inflammatory, antihistamine action. Which help to improve the patients quality of life. With there benefits “Lasunathabitha Kudineer” can be deemed as an effective drug for “Lasunathabitham” (Tonsillitis). CONCLUSION: The Global burden of Tonsillitis in children increasing prevalence and its impact in reducing the quality of life in children has prompted the author to choose an effective drug without any side effects, it is believed to improve the quality of life in children. • The trial drugs are safe to the children. • The treatment of Lasunathabitham with Lasunathabitha Kudineer has showed Good response with no adverse effect and ensure to be safe, effective and simple to administration. • The trial drugs are in easy form of preparation. • The ingredients of trial drug are feasible and useful, these compounds may serves as potentially useful drug at lower cost. • Clinical results were found to be significant good improvement was found in 72.5% of cases, Moderate in 20% of cases and mild in 7.5% of cases. Therefore it is concluded that the trial drug “Lasunathabitha kudineer” along with the modalities of Pranayama proves to be excellent in attack the tonsillitis among children.
| Item Type: | Thesis (Masters) |
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| Additional Information: | (Reg.No. 321314008) |
| Uncontrolled Keywords: | Tonsillitis ; Lasunathabitham ; Lasunathabitha Kudineer. |
| Subjects: | AYUSH > Kuzhanthai Maruthuvam |
| Depositing User: | Subramani R |
| Date Deposited: | 28 Jun 2017 02:07 |
| Last Modified: | 29 Dec 2018 16:48 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/482 |
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