Naveenkumar, - (2016) Method Development and validation of Clindamycin and Miconazole Nitrate in Soft Gelatin Capsules by RP-HPLC. Masters thesis, Edayathangudy.G.S Pillay College of Pharmacy, Nagapattinam.
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Abstract
AIM & OBJECTIVE: There were no methods have been reported in the literature for the estimation of my method. Hence we made an attempt to develop a Assay method by HPLC for the estimation of Clindamycin, and Miconazole nitrate in Clindamycin 100mg and Miconazole nitrate 200mg Capsules (finished product) to demonstrate that the analytical procedure is suitable for its intended purpose. The report applies to analytical method validation of Clindamycin and Miconazole CONCLUSION : The proposed analytical method is simple, economical, rapid, reproducible and accurate for the estimation of Clindamycin and Miconazole nitrate Capsules. A newer RP-HPLC method was developed for formulations. The proposed method gives reliable assay results with short analysis time using mobile phase of sodium acetate tri hydrate , acetonitrile ðanol.. The above method does not suffer from any interference due to common excipients or degradation products. Thus it was show that proposed methods could be successfully applied to estimate commercial pharmaceutical products containing Clindamycin and Miconazole nitrate. Thus the above studies and findings will enable the quantification of the drug for future investigation in the field of analytical chemistry. nitrate, in Clindamycin 100mg and Miconazole nitrate 200mg Capsules.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Clindamycin ; Miconazole Nitrate ; Soft Gelatin Capsules ; RP-HPLC |
| Subjects: | PHARMACY > Pharmaceutical Analysis |
| Depositing User: | Ravindran C |
| Date Deposited: | 21 Dec 2017 06:11 |
| Last Modified: | 21 Dec 2017 06:11 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/4648 |
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