A Correlative Cytological and Histopathological Study on Lesions of Salivary Gland.

Malliga, S (2007) A Correlative Cytological and Histopathological Study on Lesions of Salivary Gland. Masters thesis, Madurai Medical College.

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Abstract

Salivary Glands Are Unique Amongst The Secretory Glands, With Most Heterogenous Group Of Tumors, Exhibiting Greatest Histological Diversity. Bland Sutton Aptly Said “Tumors Of The Salivary Gland Are A Pathological Puzzle And A Source Of Unsatisfactory Speculation”. A Swelling Involving The Salivary Gland May Be As A Result Of Inflammation, Cyst Or Neoplasm. 30% Of Parotid Masses And 85% Of Submandibular Masses Are Non-Neoplastic. Tumors Of Salivary Glands Are Uncommon And Comprise Less Than 3% Of All Tumors Of Head And Neck. The Nature Of The Lesion Cannot Be Determined On Clinical Examination And Therefore Pathological Examination Is Required For Definite Diagnosis In Suspected Cases Of Neoplastic Disease. Nowadays Fine Needle Aspiration Cytology Has Emerged As An Effective And Sensitive Technique In The Diagnosis Of Lesions Of Major Or Minor Salivary Glands. Fna Is Virtually Risk Free, Simple, Rapid, Inexpensive Technique And Provides The Clinician A Definite Preoperative Diagnosis And Thus Can Facilitate Further Management. The Usefulness Of Fna In Salivary Gland Lesions Was First Observed By Karolinska Group Nearly 30 Years Ago Who Documented The Diagnostic Accuracy Of Fna In A Large Series Of Cases. Salivary Glands Are Generally Not Subjected To Incisional Or Core Biopsy Because Of The Possible Risk Of Fistula, Facial Nerve Injury And Tumor Implantation In The Cases Of Neoplasms. In The Present Study, The Utility Of Fna Cytology In The Diagnosis Of Salivary Gland Enlargement Was Studied By Correlating The Cytological Findings With The Histopathological Features. Diagnostic Accuracy, Specificity And Sensitivity Were Evaluated. The Diagnostic Pitfalls Of Fna Of Salivary Lesions Were Identified And The Possible Ways To Rectify The Misdiagnosis Were Proposed. In Addition, The Recent Literature Regarding Epidemiology, Clinical Features, Cytopathology And Histomorphology Of Salivary Gland Lesions Were Reviewed.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Cytological; Histopathological Lesions; Salivary Gland.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 27 Jun 2017 11:17
Last Modified: 27 Jun 2017 11:17
URI: http://repository-tnmgrmu.ac.in/id/eprint/464

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