Evaluation of Upper Gastrointestinal Biopsy Lesions with Special Reference to Helicobacter Pylori Infection.

Selvanayaki, K M (2010) Evaluation of Upper Gastrointestinal Biopsy Lesions with Special Reference to Helicobacter Pylori Infection. Masters thesis, Madurai Medical College.


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Upper Gastrointestinal Tract Includes The Oesophagus, Stomach And Duodenum. Patients With Diseases Of Upper Gastrointestinal System Generally Present With Symptoms Of Dysphagia, Abdominal Pain, Vomiting And Hematemesis. Upper Gastrointestinal (GI) Endoscopy Is A Diagnostic Procedure That Visualizes The Upper Part Of The Gastrointestinal Tract Upto The Duodenum. It Is An Established Mode Of Investigation And Treatment Of Wide Range Of Upper Gastrointestinal Conditions. It Has Replaced Upper GI Radiography As The Primary Method Of Diagnosing Upper GI Illness. Helicobacter Pylori (H.Pylori) Is A Spiral Shaped Organism Associated With Gastrointestinal Disease In Humans. It Causes A Chronic Gastric Infection That Usually Is Life Long And Many Epidemiologic Studies Have Shown That This Is Probably One Of The Most Common Bacterial Infection Throughout The World, Involving 40% To 50% Of The Population In Developed Countries And 80% To 90% Of The Population In Developing Regions.88 Over 80% Of Individuals Infected With This Bacterium Are Asymptomatic. It Causes A Chronic Low-Level Inflammation Of The Stomach. The Clinical Outcomes Associated With H.Pylori Infection Include Duodenal Ulcer, Gastric Ulcer, Gastric Adenocarcinoma And Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma. The Bacterium Has Been Classified As A Class I Definite Gastric Carcinogen To Human.42 H.Pylori Infection Can Be Diagnosed By Invasive (I.E., Requiring Endoscopy) And Non-Invasive Techniques (I.E., Techniques That Do Not Require Endoscopy With Biopsy Sampling).54 Eradication Of H.Pylori Improved Markedly The Inflammatory Cell Infiltration Characteristic Of H.Pylori Related Gastritis, Inhibited Recurrence Of Peptic Ulcer68 And Also Led To Regression Of MALT Lymphoma.59 In This Study The Various Methods Of Identification Of H.Pylori And The Histopahological Features Associated With H.Pylori In The Gastric Mucosa In Patients Presenting With Dyspepsia Are Discussed.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Upper Gastrointestinal Biopsy Lesions ; Special Reference Helicobacter Pylori Infection.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 27 Jun 2017 11:25
Last Modified: 27 Jun 2017 11:25
URI: http://repository-tnmgrmu.ac.in/id/eprint/443

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