Study of association of urogenital infection as a risk factor for preterm labour: A case control study

Agila Raththi, N (2017) Study of association of urogenital infection as a risk factor for preterm labour: A case control study. Masters thesis, Kilpauk Medical College, Chennai.

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Abstract

Purpose Preterm labor is a leading cause of neonatal morbidity and mortality. Ascending lower genital tract infection leads to preterm labor and adverse pregnancy outcomes. This prospective case-control study was performed to see the association between preterm labor and urogenital infections. AIM OF THE STUDY : To find out the association of urogenital infection as a risk factor for spontaneous preterm delivery. METHODS : A total of 100 women were observed for urogenital infections and their association with preterm labor. Case Group I included 50 women with preterm labor after 28 weeks and before 37 completed weeks of gestation with or without rupture of membranes. Control Group II included 50 women at completed or more than 37 weeks of gestation with or without history of preterm labor, matched to the case group with respect to age and parity. Midstream urine was sent for cytology and culture sensitivity. Samples from posterior fornix of vagina were taken with two sterilized swabs under direct vision using Cusco/Sims speculum before first vaginal examination and were studied for gram stain characteristics and culture sensitivity by standard methods. Microorganisms isolated on culture were noted, and antibiotics were given according to sensitivity. Data collected were analyzed according to the groups by chi square test and Fishers Exact categorical variables. Continuous variables were analysed using unpaired t test. RESULTS : In my study, urogenital infection was seen in 18 women in Case Group I (36 %) compared with 6 women in Control Group (12 %), and the difference was statistically significant (p 0.0425). CONCLUSION : Recognizing and treating the women having urogenital infections at a stage, when it has not become clinically evident, will decrease the percentage of women going into preterm labor and will improve the perinatal outcome.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Urogenital infection, Preterm labor, Case Control study.
Subjects: MEDICAL > Obstetrics and Gynaecology
Depositing User: Subramani R
Date Deposited: 18 Dec 2017 13:03
Last Modified: 05 Oct 2019 01:57
URI: http://repository-tnmgrmu.ac.in/id/eprint/4415

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