Drug Utilization Evaluation of Antibiotics at a Tertiary Care Hospital

Sanoj, Panicker (2016) Drug Utilization Evaluation of Antibiotics at a Tertiary Care Hospital. Masters thesis, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore.

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The Present Study were Drug utilization evaluation studies plays an important role in identifying the prescription pattern among the patients which helps in providing a useful information for improvement of the appropriate and effective use of antibiotics and also developing the proper protocols for the use of antibiotic in hospitals. This was a prospective observational study carried out in general medicine department over a period of 10 months enrolling 150 patients. The study was carried out to assess prescribing pattern, sensitivity pattern, adverse reaction involved and cost comparison of antibiotics prescribed in 150 patients. Also DDD/ 100bed- days and ATC of 10 commonly prescribed antibiotics were calculated. Most commonly prescribed antibiotics were Piperacillin / tazobactum followed by Ceftriaxone. During the study period 12 ADR was reported and most of adverse drug reactions (ADR) was observed in the age group of 61-80 years. The antibiotic sensitivity pattern was analysed which revealed that Klebsiella pneumonia was highly sensitive to Amikacin and Imipenem, E. coli was sensitive to Piperacillin/ tazobactum, E. faecalis was sensitive to Piperacillin/ tazobactum, gentamycin and Ofloxacin and Streptococcus. Aureus was sensitive to Imipenem, Meropenam and Ceftriaxone. The total cost was Rs. 1945.29±2175.39 for the prescribed antibiotics whereas for alternate antibiotics the cost was Rs. 1169.63±1282.04, which would help in minimising the patient’s expenditure. Clinical pharmacists and Clinicians need to play vital role in minimizing the antibiotic problems by conducting continual awareness programs regarding up-to-date prescribing guidelines in the hospital and also minimizing the antibiotic resistance. Therefore drug utilization review programme must be carried out to study the rational use of antimicrobials.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Drug Utilization ; Antibiotics ; Tertiary Care Hospital
Subjects: PHARMACY > Pharmacy Practice
Depositing User: Ravindran C
Date Deposited: 18 Dec 2017 07:47
Last Modified: 18 Dec 2017 07:47
URI: http://repository-tnmgrmu.ac.in/id/eprint/4394

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