Lakshmidevi, T (2011) A Prospective comparative study of sublingual Versus vaginal misoprostol in second trimester termination of pregnancy. Masters thesis, Madurai Medical College, Madurai.
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Abstract
This study ‟A” Prospective comparative study of sublingual versus vaginal misoprostol in second trimester termination of pregnancy is conducted in Department of Obstetrics and Gynaecology in Madurai Medical College, Madurai. The result of the analysis of the study is summed up as follows: Group A - Sublingual misoprostol – 50 patients, Group B - Vaginal misoprostol – 50 patients. 70% of the patients were between 20- 29 years of age in sublingual and 72% in vaginal group. All patients belong to lower socio-economic status. 86% of the patients were multigravida in sublingual group and 84% in vaginal group. Mean gestational age is (16.4 + 2.4 weeks) in sublingual group and (16.2 + 2.6 weeks) in vaginal group. There is no statistically significant difference in age, socio economic status parity and gestational age in weeks between sublingual and vaginal misoprostol groups. Induction to Abortion interval is shorter in sublingual group (11.4 + 4.9 hours) than vaginal group (15.4 + 5 hours) and is statistically significant. There is no statistically significant difference in success rate between sublingual and vaginal group. There is no statistical significance of age in relation to Induction outcome. (p = 0.1215) There is no statistical significance of parity in relation to Induction outcome.(p = 0.3435) Side effects occurred in less number of patients. 10% in sublingual group and 14% in vaginal group. The change in Hemoglobin value before and after expulsion is not statistically significant between sublingual and vaginal group. CONCLUSION: Misoprostol is equally effective in both sublingual and vaginal route in inducing second trimester abortion. Expulsion is more rapid with sublingual misoprostol than vaginal misoprostol. Misoprostol is a safe drug with minimal side effects.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Prospective comparative study ; sublingual ; vaginal misoprostol ; second trimester termination ; pregnancy. |
| Subjects: | MEDICAL > Obstetrics and Gynaecology |
| Depositing User: | Subramani R |
| Date Deposited: | 05 Dec 2017 02:46 |
| Last Modified: | 05 Dec 2017 02:46 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/4254 |
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