Maternal and fetal outcome in early onset severe preeclampsia

Divyaradha, K S (2014) Maternal and fetal outcome in early onset severe preeclampsia. Masters thesis, Madras Medial College, Chennai.


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OBJECTIVE: To study the maternal and fetal outcome in early onset severe preeclampsia and to note the variable factors associated with maternal and fetal morbidity and mortality. STUDY DESIGN: It was a prospective analytical study conducted at Institute of Obstetrics and Gynaecology with a sample size of 150 patients who had severe preeclampsia between 24 to 34 weeks. METHODS: Patients who met the inclusion criteria were included in the study. Detailed history, examination and investigations were done. Details regarding the treatment and the mode of termination are noted. Follow up of mother and neonate done upto discharge / death. RESULTS: More common in Primigravida in the age group of 21-30 years. Mean gestational age at diagnosis was 31 weeks. Most of the women underwent termination after 32 weeks 84(56%).Maternal indication was found to be the most common cause for termination in 128 (85.3%)women, Imminent eclampsia being commonest.104(69%) had caesarean section.32 women in the study group underwent expectant management with maximum prolongation of 25 days.There were no maternal death in patients who were managed expectantly but 4 patients had morbidity and there were 2 fetal mortality and 9 morbidity in the expectant management group. Mean birthweight was 1.43 kg.Out of 150 babies 90(60%) had complications. There were 16 neonatal death and 4 stillbirth with perinatal mortality rate of 30%. 58 (38.6%) women of the total study group experienced complication.Eclampsia and abruption were higher.There were 6(4%) maternal death. Mean postpartum hospital stay was 16 days. CONCLUSION: Early onset severe preeclampsia is associated with significant maternal and fetal complications Decision regarding termination of pregnancy has to be taken based on both maternal and fetal factors. Termination should be done irrespective of fetal maturity in case of severe uncontrolled blood pressure with complications. In selected cases expectant management in a tertiary care centre limit the impact of serious maternal and fetal complications.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Early onset severe preeclampsia ; Imminent Eclampsia ; Expectant management ; Maternal outcome ; Fetal outcome ; Perinatal mortality.
Subjects: MEDICAL > Obstetrics and Gynaecology
Depositing User: Subramani R
Date Deposited: 25 Nov 2017 02:39
Last Modified: 25 Nov 2017 02:39

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