Routine Antenatal Screening with Glucose Challenge Test and its Relation with Perinatal Outcome

Seetha, Panicker (2006) Routine Antenatal Screening with Glucose Challenge Test and its Relation with Perinatal Outcome. Masters thesis, PSG Institute of Medical Sciences and Research, Coimbatore.


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INTRODUCTION: Pregnancy is time when serial metabolic changes in mother are carefully regulated so as to provide optimum substrate to both mother and foetus. Subtle perturbation in maternal metabolism can have implication not only for index pregnancy but also for the future generation. Diabetes is one of the commonest medical complication of pregnancy. Patients can be separated into those who were known to have diabetes before pregnancy (overt) and those diagnosed during pregnancy (gestational). GDM is defined as carbohydrate intolerance of varying severity with onset or first recognition during pregnancy. GDM as a concept began in 1964 when O’ Sullivan and Mahan performed a 100gm 3 hour GTT on 752 pregnant women with atleast two values above two standard deviation. GDM is risk factor for the mother and the foetus. The risk increase proportionally to the maternal blood sugar concentration along a glycaemic continuum. Various screening and diagnostic tests are used. The need to screen the GDM as a risk factor in the whole population of pregnant woman has lead us to propose the use of simple, universally applied test constituted by glucose challenge test. AIM OF STUDY: 1. To do routine antenatal screening with glucose challenge test and to study the incidence of GDM in the study group and positive predictive value of GCT in pregnant women attending antenatal OP of PSGIMS&R during a period of July 2004 – July 2005. 2. To study the incidence of GCT positive GTT negative patients (false positive GCT). 3. To study the validity of GCT in diagnosing GDM. 4. To study the maternal and perinatal outcomes in both GCT positive GTT negative patients and GDM patients. 5. To compare perinatal outcomes between patients with GCT+ GTT- patients and patients with normal GCT. MATERIALS AND METHODS: A prospective study was carried out in pregnant women attending antenatal op in PSGIMS&R and all of them were followed till delivery to assess the maternal and perinatal outcomes. SELECTION CRITERIA: Pregnant women attending antenatal OPD were recruited for the study INCLUSION CRITERIA:

Item Type: Thesis (Masters)
Uncontrolled Keywords: Routine Antenatal Screening ; Glucose Challenge Test ; Perinatal Outcome.
Subjects: MEDICAL > Obstetrics and Gynaecology
Depositing User: Subramani R
Date Deposited: 25 Nov 2017 02:28
Last Modified: 25 Nov 2017 02:28

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