Kavitha, N (2014) A study on serum anticardiolipin antibody in pseudoexfoliation. Masters thesis, PSG Institute of Medical Sciences & Research, Coimbatore.
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Abstract
AIM OF THE STUDY: 1. To evaluate the levels of anticardiolipin antibodies in patients with pseudoexfoliation and controls. 2. To assess the association between pseudoexfoliation and cardiovascular disease. MATERIAL AND METHODS: This is a prospective study to evaluate the levels of anticardiolipin antibody in patients with pseudoexfoliation. This study included 30 patients with pseudoexfoliation and 30 healthly controls with comparable age and gender with no comorbities. All patients underwent a complete ophthalmic examination , after pseudoexfoliation was diagnosed. Echocardiography was done to know the cardiovascular status of the patients in 2 groups. Serum anticardiolipin antibodies IgG and IgM was done by using ELISA method in both cases and control groups. RESULTS: We found elevated serum levels of anticardiolipin (IgG and IgM) antibody in patients with pseudoexfoliation. The mean level of acl IgG and IgM level in patients with pseudoexfoliation were statistically significant(p value <0.05). CONCLUSIONS: Elevated levels of anticardiolipin antibody is a risk factor for cardiovascular problems. Hence the attending ophthalmologist will be able to intimate the attending physician about the possible cardiac risk association.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Pseudoexfoliation ; True efoliation ; Anticardiolipin antibody ; endothelial dysfunction. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Devi S |
| Date Deposited: | 12 Dec 2017 05:49 |
| Last Modified: | 24 Jun 2018 14:00 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3985 |
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